{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["88(6)"],"submitter":["Ryndock E"],"funding":["Nanosonics Ltd"],"pubmed_abstract":["Ultrasound probes used in endocavitary procedures have been shown to be contaminated with high-risk HPV after routine use and HPV is also known to be resistant to some high level disinfectants (HLDs). This study compared efficacy of two leading ultrasound probe HLD methods; liquid ortho-phthalaldehyde (Cidex® OPA) and an automated device using sonicated hydrogen peroxide (trophon® EPR) against HPV16 and HPV18 in a hard-surface carrier test. Native HPV16 and HPV18 virions were generated in organotypic epithelial raft cultures. Viral lysates were dried onto carriers with a 5% (v/v) protein soil. Efficacy tests were performed against the automated device at 35% and 31.5% H2 O2 and 0.55% OPA in quadruplicate with matched input, neutralization, and cytotoxicity controls. Hypochlorite was includ"],"journal":["Journal of medical virology"],"pagination":["1076-80"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5063110"],"repository":["biostudies-literature"],"pubmed_title":["Susceptibility of HPV16 and 18 to high level disinfectants indicated for semi-critical ultrasound probes."],"pmcid":["PMC5063110"],"pubmed_authors":["Robison R","Meyers C","Ryndock E"],"additional_accession":[]},"is_claimable":false,"name":"Susceptibility of HPV16 and 18 to high level disinfectants indicated for semi-critical ultrasound probes.","description":"Ultrasound probes used in endocavitary procedures have been shown to be contaminated with high-risk HPV after routine use and HPV is also known to be resistant to some high level disinfectants (HLDs). This study compared efficacy of two leading ultrasound probe HLD methods; liquid ortho-phthalaldehyde (Cidex® OPA) and an automated device using sonicated hydrogen peroxide (trophon® EPR) against HPV16 and HPV18 in a hard-surface carrier test. Native HPV16 and HPV18 virions were generated in organotypic epithelial raft cultures. Viral lysates were dried onto carriers with a 5% (v/v) protein soil. Efficacy tests were performed against the automated device at 35% and 31.5% H2 O2 and 0.55% OPA in quadruplicate with matched input, neutralization, and cytotoxicity controls. Hypochlorite was includ","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Jun","modification":"2025-04-04T09:21:06.461Z","creation":"2019-03-27T02:26:35Z"},"accession":"S-EPMC5063110","cross_references":{"pubmed":["26519866"],"doi":["10.1002/jmv.24421"]}}