{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Shen F"],"funding":["Division of Chemistry","American Chemical Society","National Institute of General Medical Sciences","NIGMS NIH HHS"],"pagination":["1554-7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5080616"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(7)"],"pubmed_abstract":["Bismuth(III) acetate is a safe, inexpensive, and selective facilitator of sequential protodeboronations, which when used in conjunction with Ir-catalyzed borylations allows access to a diversity of borylated indoles. The versatility of combining Ir-catalyzed borylations with Bi(III)-catalyzed protodeboronation is demonstrated by selectively converting 6-fluoroindole into products with Bpin groups at the 4-, 5-, 7-, 2,7-, 4,7-, 3,5-, and 2,4,7-positions and the late-stage functionalization of sumatriptan."],"journal":["Organic letters"],"pubmed_title":["Bismuth Acetate as a Catalyst for the Sequential Protodeboronation of Di- and Triborylated Indoles."],"pmcid":["PMC5080616"],"funding_grant_id":["R01 GM063188","1012883","GM63188","R56 GM063188"],"pubmed_authors":["Maleczka RE","Tyagarajan S","Smith MR","Perera D","Maligres PE","Krska SW","Shen F"],"additional_accession":[]},"is_claimable":false,"name":"Bismuth Acetate as a Catalyst for the Sequential Protodeboronation of Di- and Triborylated Indoles.","description":"Bismuth(III) acetate is a safe, inexpensive, and selective facilitator of sequential protodeboronations, which when used in conjunction with Ir-catalyzed borylations allows access to a diversity of borylated indoles. The versatility of combining Ir-catalyzed borylations with Bi(III)-catalyzed protodeboronation is demonstrated by selectively converting 6-fluoroindole into products with Bpin groups at the 4-, 5-, 7-, 2,7-, 4,7-, 3,5-, and 2,4,7-positions and the late-stage functionalization of sumatriptan.","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Apr","modification":"2025-04-04T08:29:03.671Z","creation":"2019-03-27T02:27:32Z"},"accession":"S-EPMC5080616","cross_references":{"pubmed":["26998615"],"doi":["10.1021/acs.orglett.6b00356"]}}