{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang Y"],"funding":["Administration Office of Heilongjiang Postdoctoral Program","Fund of Innovative Talents of the Heilongjiang University of Chinese Medicine"],"pagination":["e0164652"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5120789"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(11)"],"pubmed_abstract":["The peripheral nervous system may play an important role in normal bone maintenance and remodeling. Substance P (SP) is a neuropeptide associated with bone loss and formation that may mediate the effects of the nervous system. The purpose of this study is to determine if treadmill running combined with electro-acupuncture at Jiaji acupoints (Jiaji-EA) affects tibial bone mass and SP expression in rabbits with sciatic nerve injury. Twenty-four juvenile male New Zealand white rabbits were randomly assigned to one of 4 groups: sham injury control (sham), sciatic never crush control (SNCr), treadmill running (treadmill), and Jiaji-EA combined with treadmill running (ET group). The SNCr, treadmill, and ET groups all had an induced sciatic never crush injury of approximately 2mm. Control groups "],"journal":["PloS one"],"pubmed_title":["Effects of Treatment of Treadmill Combined with Electro-Acupuncture on Tibia Bone Mass and Substance PExpression of Rabbits with Sciatic Nerve Injury."],"pmcid":["PMC5120789"],"funding_grant_id":["051290","LBH-Z13202"],"pubmed_authors":["Koleini M","Tang Q","Zhu L","Huang L","Wang Y","Zou D","Huang R"],"additional_accession":[]},"is_claimable":false,"name":"Effects of Treatment of Treadmill Combined with Electro-Acupuncture on Tibia Bone Mass and Substance PExpression of Rabbits with Sciatic Nerve Injury.","description":"The peripheral nervous system may play an important role in normal bone maintenance and remodeling. Substance P (SP) is a neuropeptide associated with bone loss and formation that may mediate the effects of the nervous system. The purpose of this study is to determine if treadmill running combined with electro-acupuncture at Jiaji acupoints (Jiaji-EA) affects tibial bone mass and SP expression in rabbits with sciatic nerve injury. Twenty-four juvenile male New Zealand white rabbits were randomly assigned to one of 4 groups: sham injury control (sham), sciatic never crush control (SNCr), treadmill running (treadmill), and Jiaji-EA combined with treadmill running (ET group). The SNCr, treadmill, and ET groups all had an induced sciatic never crush injury of approximately 2mm. Control groups ","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016","modification":"2025-04-27T01:24:44.295Z","creation":"2019-03-26T22:48:53Z"},"accession":"S-EPMC5120789","cross_references":{"pubmed":["27880769"],"doi":["10.1371/journal.pone.0164652"]}}