{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang H"],"funding":["Science and Technology Planning Project of Guangdong Province to Wenting Zeng"],"pagination":["3417976"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5141322"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2016"],"pubmed_abstract":["<i>Background</i>. The inconsistent finding was between hepatitis B virus (HBV) infections and cholangiocarcinoma (CCA). This meta-analysis is to explore this relationship in Asia. <i>Methods</i>. A literature search was performed using PubMed, Web of Science, and Cochrane Library to October 30, 2015. Pooled incidence rate and OR with 95% CI were calculated using STATA 11.0. <i>Results</i>. Thirty-nine studies were included. The pooled incidence rate of CCA patients with HBV infection was 31% (95% CI 22%-39%). The pooled OR showed increased risk of CCA incidence with HBV infection (OR = 2.72, 95% CI 1.90-3.88), especially in ICC (OR = 3.184, 95% CI 2.356-4.302), while it showed no risk in ECC (OR = 1.407, 95% CI 0.925-2.141). Also, the pooled OR showed increased risk of ICC and ECC inciden"],"journal":["BioMed research international"],"pubmed_title":["HBV Infection Status and the Risk of Cholangiocarcinoma in Asia: A Meta-Analysis."],"pmcid":["PMC5141322"],"funding_grant_id":["2013B022000101"],"pubmed_authors":["Zhang H","Liang J","Zhu B","Zeng W"],"additional_accession":[]},"is_claimable":false,"name":"HBV Infection Status and the Risk of Cholangiocarcinoma in Asia: A Meta-Analysis.","description":"<i>Background</i>. The inconsistent finding was between hepatitis B virus (HBV) infections and cholangiocarcinoma (CCA). This meta-analysis is to explore this relationship in Asia. <i>Methods</i>. A literature search was performed using PubMed, Web of Science, and Cochrane Library to October 30, 2015. Pooled incidence rate and OR with 95% CI were calculated using STATA 11.0. <i>Results</i>. Thirty-nine studies were included. The pooled incidence rate of CCA patients with HBV infection was 31% (95% CI 22%-39%). The pooled OR showed increased risk of CCA incidence with HBV infection (OR = 2.72, 95% CI 1.90-3.88), especially in ICC (OR = 3.184, 95% CI 2.356-4.302), while it showed no risk in ECC (OR = 1.407, 95% CI 0.925-2.141). Also, the pooled OR showed increased risk of ICC and ECC inciden","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016","modification":"2025-04-21T20:17:35.327Z","creation":"2019-03-27T02:30:54Z"},"accession":"S-EPMC5141322","cross_references":{"pubmed":["27999794"],"doi":["10.1155/2016/3417976"]}}