biostudies-literatureZhang HScience and Technology Planning Project of Guangdong Province to Wenting Zeng3417976https://www.ebi.ac.uk/biostudies/studies/S-EPMC5141322biostudies-literatureUnknown2016<i>Background</i>. The inconsistent finding was between hepatitis B virus (HBV) infections and cholangiocarcinoma (CCA). This meta-analysis is to explore this relationship in Asia. <i>Methods</i>. A literature search was performed using PubMed, Web of Science, and Cochrane Library to October 30, 2015. Pooled incidence rate and OR with 95% CI were calculated using STATA 11.0. <i>Results</i>. Thirty-nine studies were included. The pooled incidence rate of CCA patients with HBV infection was 31% (95% CI 22%-39%). The pooled OR showed increased risk of CCA incidence with HBV infection (OR = 2.72, 95% CI 1.90-3.88), especially in ICC (OR = 3.184, 95% CI 2.356-4.302), while it showed no risk in ECC (OR = 1.407, 95% CI 0.925-2.141). Also, the pooled OR showed increased risk of ICC and ECC incidenBioMed research internationalHBV Infection Status and the Risk of Cholangiocarcinoma in Asia: A Meta-Analysis.PMC51413222013B022000101Zhang HLiang JZhu BZeng WfalseHBV Infection Status and the Risk of Cholangiocarcinoma in Asia: A Meta-Analysis.<i>Background</i>. The inconsistent finding was between hepatitis B virus (HBV) infections and cholangiocarcinoma (CCA). This meta-analysis is to explore this relationship in Asia. <i>Methods</i>. A literature search was performed using PubMed, Web of Science, and Cochrane Library to October 30, 2015. Pooled incidence rate and OR with 95% CI were calculated using STATA 11.0. <i>Results</i>. Thirty-nine studies were included. The pooled incidence rate of CCA patients with HBV infection was 31% (95% CI 22%-39%). The pooled OR showed increased risk of CCA incidence with HBV infection (OR = 2.72, 95% CI 1.90-3.88), especially in ICC (OR = 3.184, 95% CI 2.356-4.302), while it showed no risk in ECC (OR = 1.407, 95% CI 0.925-2.141). Also, the pooled OR showed increased risk of ICC and ECC inciden2016-01-01T00:00:00Z20162025-04-21T20:17:35.327Z2019-03-27T02:30:54ZS-EPMC51413222799979410.1155/2016/3417976