{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Scott KM"],"funding":["NIDA NIH HHS","FIC NIH HHS","NIMH NIH HHS"],"pagination":["3161-3172"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5206971"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["46(15)"],"pubmed_abstract":["<h4>Background</h4>This is the first cross-national study of intermittent explosive disorder (IED).<h4>Method</h4>A total of 17 face-to-face cross-sectional household surveys of adults were conducted in 16 countries (n = 88 063) as part of the World Mental Health Surveys initiative. The World Health Organization Composite International Diagnostic Interview (CIDI 3.0) assessed DSM-IV IED, using a conservative definition.<h4>Results</h4>Lifetime prevalence of IED ranged across countries from 0.1 to 2.7% with a weighted average of 0.8%; 0.4 and 0.3% met criteria for 12-month and 30-day prevalence, respectively. Sociodemographic correlates of lifetime risk of IED were being male, young, unemployed, divorced or separated, and having less education. The median age of onset of IED was 17 years with an interquartile range across countries of 13-23 years. The vast majority (81.7%) of those with lifetime IED met criteria for at least one other lifetime disorder; co-morbidity was highest with alcohol abuse and depression. Of those with 12-month IED, 39% reported severe impairment in at least one domain, most commonly social or relationship functioning. Prior traumatic experiences involving physical (non-combat) or sexual violence were associated with increased risk of IED onset.<h4>Conclusions</h4>Conservatively defined, IED is a low prevalence disorder but this belies the true societal costs of IED in terms of the effects of explosive anger attacks on families and relationships. IED is more common among males, the young, the socially disadvantaged and among those with prior exposure to violence, especially in childhood."],"journal":["Psychological medicine"],"pubmed_title":["The cross-national epidemiology of DSM-IV intermittent explosive disorder."],"pmcid":["PMC5206971"],"funding_grant_id":["R01 MH061905","R01 DA016558","R01 MH070884","R13 MH066849","U01 MH060220","R01 MH069864","K05 DA015799","R01 MH059575","R03 TW006481"],"pubmed_authors":["Karam E","Xavier M","Lee S","Viana MC","Bunting B","Florescu S","Posada-Villa J","Ferrand MP","Scott KM","Hwang I","Bromet E","Hu C","Adamowski T","Kessler RC","Stein D","Tachimori H","Al-Hamzawi A","Lim CC","Hinkov H","Gureje O"],"additional_accession":[]},"is_claimable":false,"name":"The cross-national epidemiology of DSM-IV intermittent explosive disorder.","description":"<h4>Background</h4>This is the first cross-national study of intermittent explosive disorder (IED).<h4>Method</h4>A total of 17 face-to-face cross-sectional household surveys of adults were conducted in 16 countries (n = 88 063) as part of the World Mental Health Surveys initiative. The World Health Organization Composite International Diagnostic Interview (CIDI 3.0) assessed DSM-IV IED, using a conservative definition.<h4>Results</h4>Lifetime prevalence of IED ranged across countries from 0.1 to 2.7% with a weighted average of 0.8%; 0.4 and 0.3% met criteria for 12-month and 30-day prevalence, respectively. Sociodemographic correlates of lifetime risk of IED were being male, young, unemployed, divorced or separated, and having less education. The median age of onset of IED was 17 years with an interquartile range across countries of 13-23 years. The vast majority (81.7%) of those with lifetime IED met criteria for at least one other lifetime disorder; co-morbidity was highest with alcohol abuse and depression. Of those with 12-month IED, 39% reported severe impairment in at least one domain, most commonly social or relationship functioning. Prior traumatic experiences involving physical (non-combat) or sexual violence were associated with increased risk of IED onset.<h4>Conclusions</h4>Conservatively defined, IED is a low prevalence disorder but this belies the true societal costs of IED in terms of the effects of explosive anger attacks on families and relationships. IED is more common among males, the young, the socially disadvantaged and among those with prior exposure to violence, especially in childhood.","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Nov","modification":"2024-11-20T06:31:08.269Z","creation":"2019-03-27T02:33:02Z"},"accession":"S-EPMC5206971","cross_references":{"pubmed":["27572872"],"doi":["10.1017/S0033291716001859","10.1017/s0033291716001859"]}}