biostudies-literatureChen YHong Kong Baptist UniversityInnovation and Technology Fund10-22https://www.ebi.ac.uk/biostudies/studies/S-EPMC5223068biostudies-literatureUnknown41(1)<h4>Background</h4>Asian ginseng and American ginseng are functional foods that share a close genetic relationship and are well-known worldwide. This article aims to investigate the correlation between morphological characteristics and the inherent quality of Asian and American ginsengs.<h4>Methods</h4>In this study, an ultra-HPLC-quadrupole/time-of-flight MS (UHPLC-Q/TOF-MS) method was established for the quantitative analysis of 45 ginseng samples. The method developed for determination was precise and accurate.<h4>Results</h4>The results showed that Asian ginseng samples with the same growing time (with the same or similar number of stem scars) that had a thinner main root, a longer rhizome and more branch roots contained greater amounts of ginsenosides. For American ginseng, two tendenJournal of ginseng researchDetermination of ginsenosides in Asian and American ginsengs by liquid chromatography-quadrupole/time-of-flight MS: assessing variations based on morphological characteristics.PMC5223068FRG2/12-13/030ITS/185/13FXBrand EQin MLiang ZChen YChen HZhao ZYi TfalseDetermination of ginsenosides in Asian and American ginsengs by liquid chromatography-quadrupole/time-of-flight MS: assessing variations based on morphological characteristics.<h4>Background</h4>Asian ginseng and American ginseng are functional foods that share a close genetic relationship and are well-known worldwide. This article aims to investigate the correlation between morphological characteristics and the inherent quality of Asian and American ginsengs.<h4>Methods</h4>In this study, an ultra-HPLC-quadrupole/time-of-flight MS (UHPLC-Q/TOF-MS) method was established for the quantitative analysis of 45 ginseng samples. The method developed for determination was precise and accurate.<h4>Results</h4>The results showed that Asian ginseng samples with the same growing time (with the same or similar number of stem scars) that had a thinner main root, a longer rhizome and more branch roots contained greater amounts of ginsenosides. For American ginseng, two tenden2017-01-01T00:00:00Z2017 Jan2025-04-22T19:24:28.511Z2019-03-27T02:33:43ZS-EPMC52230682812331710.1016/j.jgr.2015.12.004