{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Luciano M"],"funding":["Medical Research Council","Biotechnology and Biological Sciences Research Council"],"pagination":["449-455"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5278943"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["88(5)"],"pubmed_abstract":["<h4>Objective</h4>To assess the association between Mediterranean-type diet (MeDi) and change in brain MRI volumetric measures and mean cortical thickness across a 3-year period in older age (73-76 years).<h4>Methods</h4>We focused on 2 longitudinal brain volumes (total and gray matter; n = 401 and 398, respectively) plus a longitudinal measurement of cortical thickness (n = 323), for which the previous cross-sectional evidence of an association with the MeDi was strongest. Adherence to the MeDi was calculated from data gathered from a food frequency questionnaire at age 70, 3 years prior to the baseline imaging data collection.<h4>Results</h4>In regression models adjusting for relevant demographic and physical health indicators, we found that lower adherence to the MeDi was associated wit"],"journal":["Neurology"],"pubmed_title":["Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort."],"pmcid":["PMC5278943"],"funding_grant_id":["G1001245","G0701120","MR/N003403/1","MR/K026992/1","MR/M013111/1"],"pubmed_authors":["Valdes Hernandez MC","Deary IJ","Cox SR","Craig LC","McNeill GM","Corley J","Luciano M","Dickie DA","Karama S","Bastin ME","Wardlaw JM"],"additional_accession":[]},"is_claimable":false,"name":"Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort.","description":"<h4>Objective</h4>To assess the association between Mediterranean-type diet (MeDi) and change in brain MRI volumetric measures and mean cortical thickness across a 3-year period in older age (73-76 years).<h4>Methods</h4>We focused on 2 longitudinal brain volumes (total and gray matter; n = 401 and 398, respectively) plus a longitudinal measurement of cortical thickness (n = 323), for which the previous cross-sectional evidence of an association with the MeDi was strongest. Adherence to the MeDi was calculated from data gathered from a food frequency questionnaire at age 70, 3 years prior to the baseline imaging data collection.<h4>Results</h4>In regression models adjusting for relevant demographic and physical health indicators, we found that lower adherence to the MeDi was associated wit","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jan","modification":"2025-04-04T08:44:47.626Z","creation":"2019-03-27T02:35:14Z"},"accession":"S-EPMC5278943","cross_references":{"pubmed":["28053008"],"doi":["10.1212/WNL.0000000000003559"]}}