{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pole JD"],"funding":["NCI NIH HHS"],"pagination":["540-545"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5318976"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["116(4)"],"pubmed_abstract":["<h4>Background</h4>Objectives were to describe the proportion of deaths due to treatment-related mortality (TRM) and to identify risk factors and probable causes of TRM among paediatric cancer deaths in a population-based cohort.<h4>Methods</h4>We included children with cancer ⩽18 years diagnosed and treated in Ontario who died between January 2003 and December 2012. Deaths were identified using a provincial registry, the Pediatric Oncology Group of Ontario Networked Information System. Probable causes of TRM were described.<h4>Results</h4>Among the 964 deaths identified, 821 were included. The median age at diagnosis was 6.6 years (range 0-18.8) and 51.8% had at least one relapse. Of the deaths examined, TRM occurred in 217/821 (26.4%) while 604/821 (73.6%) were due to progressive cancer."],"journal":["British journal of cancer"],"pubmed_title":["Evaluation of treatment-related mortality among paediatric cancer deaths: a population based analysis."],"pmcid":["PMC5318976"],"funding_grant_id":["UG1 CA189955"],"pubmed_authors":["Sung L","Johnston DL","Silva M","Alexander S","Gibson P","Lazor T","Portwine C","Ethier MC","Pole JD"],"additional_accession":[]},"is_claimable":false,"name":"Evaluation of treatment-related mortality among paediatric cancer deaths: a population based analysis.","description":"<h4>Background</h4>Objectives were to describe the proportion of deaths due to treatment-related mortality (TRM) and to identify risk factors and probable causes of TRM among paediatric cancer deaths in a population-based cohort.<h4>Methods</h4>We included children with cancer ⩽18 years diagnosed and treated in Ontario who died between January 2003 and December 2012. Deaths were identified using a provincial registry, the Pediatric Oncology Group of Ontario Networked Information System. Probable causes of TRM were described.<h4>Results</h4>Among the 964 deaths identified, 821 were included. The median age at diagnosis was 6.6 years (range 0-18.8) and 51.8% had at least one relapse. Of the deaths examined, TRM occurred in 217/821 (26.4%) while 604/821 (73.6%) were due to progressive cancer.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Feb","modification":"2025-04-22T19:20:01.821Z","creation":"2019-03-26T23:01:50Z"},"accession":"S-EPMC5318976","cross_references":{"pubmed":["28095399"],"doi":["10.1038/bjc.2016.443"]}}