{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(4)"],"submitter":["Yesilyurt V"],"funding":["NIDDK NIH HHS","NCI NIH HHS","National Institutes of Health"],"pubmed_abstract":["The surface modification of implantable biomaterials with zwitterionic phosphorylcholine polymer is demonstrated through mussel-mimetic catecholamine polymer thin films. Using this method, the surfaces of alginate hydrogel microspheres and polystyrene microbeads, a model material known to produce robust foreign body responses and fibrosis, are successfully modified to reduce the tissue reaction by reducing the fibrosis in immunocompetent C57BL/6J mice."],"journal":["Advanced healthcare materials"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5322155"],"repository":["biostudies-literature"],"pubmed_title":["A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings."],"pmcid":["PMC5322155"],"funding_grant_id":["F32 DK101335","P30 CA014051","DP1 CA174420","F32DK101335"],"pubmed_authors":["Veiseh O","Anderson DG","Li J","Bose S","Xie X","Chen M","Vegas AJ","Yesilyurt V","Langer R","Webber MJ","Doloff JC","Bader AR"],"additional_accession":[]},"is_claimable":false,"name":"A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings.","description":"The surface modification of implantable biomaterials with zwitterionic phosphorylcholine polymer is demonstrated through mussel-mimetic catecholamine polymer thin films. Using this method, the surfaces of alginate hydrogel microspheres and polystyrene microbeads, a model material known to produce robust foreign body responses and fibrosis, are successfully modified to reduce the tissue reaction by reducing the fibrosis in immunocompetent C57BL/6J mice.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Feb","modification":"2025-04-04T02:08:46.584Z","creation":"2019-03-26T22:59:20Z"},"accession":"S-EPMC5322155","cross_references":{"pubmed":["27976536"],"doi":["10.1002/adhm.201601091"]}}