biostudies-literatureSkielboe AKThe Danish Heart Foundatione0170060https://www.ebi.ac.uk/biostudies/studies/S-EPMC5322948biostudies-literatureUnknown12(2)<h4>Background</h4>Physical activity at moderate-high intensity is recommended to prevent lifestyle diseases. Patients with atrial fibrillation are at risk of a sedentary lifestyle due to fear of exercise-induced episodes of atrial fibrillation. The burden of arrhythmia can be reduced by physical exercise. The effect of exercise intensity on burden of atrial fibrillation needs to be studied further.<h4>Methods and results</h4>In a 12-week randomized controlled trial, 76 patients with paroxysmal/persistent atrial fibrillation were allocated to perform exercise at either low intensity or high intensity (50% and 80% of maximal perceived exertion, respectively). Primary outcome was burden of AF measured by daily electrocardiography-reporting during 12 weeks. Secondarily, change in maximal oxygPloS oneCardiovascular exercise and burden of arrhythmia in patients with atrial fibrillation - A randomized controlled trial.PMC532294814-R97-A5061Mourier MSkielboe AKBandholm TQKallemose TDixen UHakmann SfalseCardiovascular exercise and burden of arrhythmia in patients with atrial fibrillation - A randomized controlled trial.<h4>Background</h4>Physical activity at moderate-high intensity is recommended to prevent lifestyle diseases. Patients with atrial fibrillation are at risk of a sedentary lifestyle due to fear of exercise-induced episodes of atrial fibrillation. The burden of arrhythmia can be reduced by physical exercise. The effect of exercise intensity on burden of atrial fibrillation needs to be studied further.<h4>Methods and results</h4>In a 12-week randomized controlled trial, 76 patients with paroxysmal/persistent atrial fibrillation were allocated to perform exercise at either low intensity or high intensity (50% and 80% of maximal perceived exertion, respectively). Primary outcome was burden of AF measured by daily electrocardiography-reporting during 12 weeks. Secondarily, change in maximal oxyg2017-01-01T00:00:00Z20172026-05-30T06:46:14.124Z2019-03-26T22:52:55ZS-EPMC53229482823132510.1371/journal.pone.0170060