biostudies-literatureBeasley JMNCATS NIH HHSNICHD NIH HHSNHLBI NIH HHSNCI NIH HHS3256-3264https://www.ebi.ac.uk/biostudies/studies/S-EPMC5348247biostudies-literatureUnknown19(18)<h4>Objective</h4>Measurement error in self-reported total sugars intake may obscure associations between sugars consumption and health outcomes, and the sum of 24 h urinary sucrose and fructose may serve as a predictive biomarker of total sugars intake.<h4>Design</h4>The Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS) was an ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort. Doubly labelled water and 24 h urinary sucrose and fructose were used as biomarkers of energy and sugars intake, respectively. Participants' diets were assessed by up to three 24 h recalls (88 % had two or more recalls). Procedures were repeated approximately 6 months after the initial visit among a subset of ninety-six participants.<h4>Setting</h4>Four centres (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) across the USA.<h4>Subjects</h4>Men and women (n 477) aged 18-74 years.<h4>Results</h4>The geometric mean of total sugars was 167·5 (95 % CI 154·4, 181·7) g/d for the biomarker-predicted and 90·6 (95 % CI 87·6, 93·6) g/d for the self-reported total sugars intake. Self-reported total sugars intake was not correlated with biomarker-predicted sugars intake (r=-0·06, P=0·20, n 450). Among the reliability sample (n 90), the reproducibility coefficient was 0·59 for biomarker-predicted and 0·20 for self-reported total sugars intake.<h4>Conclusions</h4>Possible explanations for the lack of association between biomarker-predicted and self-reported sugars intake include measurement error in self-reported diet, high intra-individual variability in sugars intake, and/or urinary sucrose and fructose may not be a suitable proxy for total sugars intake in this study population.Public health nutritionBiomarker-predicted sugars intake compared with self-reported measures in US Hispanics/Latinos: results from the HCHS/SOL SOLNAS study.PMC5348247P2C HD050924N01 HC065233R01 HL095856KL2 TR000461T32 HL007024UL1 TR001073N01 HC065236N01 HC065237N01 HC065234N01 HC065235P30 CA071789Stamler JStoutenberg MWylie-Rosett JTasevska NKizer JRBeasley JMWong WWSotres-Alvarez DShaw PAFranke AASiega-Riz AMMossavar-Rahmani YJung MGellman MDVan Horn LfalseBiomarker-predicted sugars intake compared with self-reported measures in US Hispanics/Latinos: results from the HCHS/SOL SOLNAS study.<h4>Objective</h4>Measurement error in self-reported total sugars intake may obscure associations between sugars consumption and health outcomes, and the sum of 24 h urinary sucrose and fructose may serve as a predictive biomarker of total sugars intake.<h4>Design</h4>The Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS) was an ancillary study to the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) cohort. Doubly labelled water and 24 h urinary sucrose and fructose were used as biomarkers of energy and sugars intake, respectively. Participants' diets were assessed by up to three 24 h recalls (88 % had two or more recalls). Procedures were repeated approximately 6 months after the initial visit among a subset of ninety-six participants.<h4>Setting</h4>Four centres (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) across the USA.<h4>Subjects</h4>Men and women (n 477) aged 18-74 years.<h4>Results</h4>The geometric mean of total sugars was 167·5 (95 % CI 154·4, 181·7) g/d for the biomarker-predicted and 90·6 (95 % CI 87·6, 93·6) g/d for the self-reported total sugars intake. Self-reported total sugars intake was not correlated with biomarker-predicted sugars intake (r=-0·06, P=0·20, n 450). Among the reliability sample (n 90), the reproducibility coefficient was 0·59 for biomarker-predicted and 0·20 for self-reported total sugars intake.<h4>Conclusions</h4>Possible explanations for the lack of association between biomarker-predicted and self-reported sugars intake include measurement error in self-reported diet, high intra-individual variability in sugars intake, and/or urinary sucrose and fructose may not be a suitable proxy for total sugars intake in this study population.2016-01-01T00:00:00Z2016 Dec2026-06-03T18:42:18.957Z2025-04-06T02:35:53.405ZS-EPMC53482472733907810.1017/S136898001600158010.1017/s1368980016001580