biostudies-literatureChen DNational Natural Science Foundation of China1601-1606https://www.ebi.ac.uk/biostudies/studies/S-EPMC5361865biostudies-literatureUnknown8(2)An environmentally benign method for C-H/O-H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C-S and C-O bond formations with broad substrate scope.Chemical scienceMetal-free O-H/C-H difunctionalization of phenols by <i>o</i>-hydroxyarylsulfonium salts in water.PMC536186521502094Cai XMHuang SYang YWang FChen DFeng QfalseMetal-free O-H/C-H difunctionalization of phenols by <i>o</i>-hydroxyarylsulfonium salts in water.An environmentally benign method for C-H/O-H difunctionalization of phenols with sulfoxides under mild conditions has been developed. The reaction process is mediated by an electrophilic aromatic substitution and subsequent selective aryl or alkyl migration, involving C-S and C-O bond formations with broad substrate scope.2017-01-01T00:00:00Z2017 Feb2025-04-05T15:14:06.956Z2019-03-27T02:39:16ZS-EPMC53618652845128910.1039/c6sc04504a