{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dinakarpandian D"],"funding":["NIBIB NIH HHS"],"pagination":["2"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC539358"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["4(1)"],"pubmed_abstract":["BACKGROUND: The amino acid composition of a low molecular weight chromium binding peptide (LMWCr), isolated from bovine liver, is reportedly E:G:C:D::4:2:2:2, though its sequence has not been discovered. There is some controversy surrounding the exact biochemical forms and the action of Cr(III) in biological systems; the topic has been the subject of many experimental reports and continues to be investigated. Clarification of Cr-protein interactions will further understanding Cr(III) biochemistry and provide a basis for novel therapies based on metallocomplexes or small molecules. RESULTS: A genomic search of the non-redundant database for all possible decapeptides of the reported composition yields three exact matches, EDGEECDCGE, DGEECDCGEE and CEGGCEEDDE. The first two sequences are fou"],"journal":["BMC chemical biology"],"pubmed_title":["An informatics search for the low-molecular weight chromium-binding peptide."],"pmcid":["PMC539358"],"funding_grant_id":["P41 EB001980"],"pubmed_authors":["Van Horn JD","Amini K","Chaudhary S","Bennett B","Dinakarpandian D","Morrissette V"],"additional_accession":[]},"is_claimable":false,"name":"An informatics search for the low-molecular weight chromium-binding peptide.","description":"BACKGROUND: The amino acid composition of a low molecular weight chromium binding peptide (LMWCr), isolated from bovine liver, is reportedly E:G:C:D::4:2:2:2, though its sequence has not been discovered. There is some controversy surrounding the exact biochemical forms and the action of Cr(III) in biological systems; the topic has been the subject of many experimental reports and continues to be investigated. Clarification of Cr-protein interactions will further understanding Cr(III) biochemistry and provide a basis for novel therapies based on metallocomplexes or small molecules. RESULTS: A genomic search of the non-redundant database for all possible decapeptides of the reported composition yields three exact matches, EDGEECDCGE, DGEECDCGEE and CEGGCEEDDE. The first two sequences are fou","dates":{"release":"2004-01-01T00:00:00Z","publication":"2004 Dec","modification":"2026-05-03T18:48:22.286Z","creation":"2019-03-27T01:08:26Z"},"accession":"S-EPMC539358","cross_references":{"pubmed":["15603587"],"doi":["10.1186/1472-6769-4-2"]}}