{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(1)"],"submitter":["LeBlanc BW"],"pubmed_abstract":["We tested the relation between pain behavior, theta (4-8?Hz) oscillations in somatosensory cortex and burst firing in thalamic neurons in vivo. Optically-induced thalamic bursts attenuated cortical theta and mechanical allodynia. It is proposed that thalamic bursts are an adaptive response to pain that de-synchronizes cortical theta and decreases sensory salience."],"journal":["Scientific reports"],"pagination":["2482"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5449396"],"repository":["biostudies-literature"],"pubmed_title":["Thalamic Bursts Down-regulate Cortical Theta and Nociceptive Behavior."],"pmcid":["PMC5449396"],"pubmed_authors":["Roach C","Xia J","Koyama S","Chao YC","Saab CY","Moore CI","Smith KA","Cross B","Levitt J","LeBlanc BW"],"additional_accession":[]},"is_claimable":false,"name":"Thalamic Bursts Down-regulate Cortical Theta and Nociceptive Behavior.","description":"We tested the relation between pain behavior, theta (4-8?Hz) oscillations in somatosensory cortex and burst firing in thalamic neurons in vivo. Optically-induced thalamic bursts attenuated cortical theta and mechanical allodynia. It is proposed that thalamic bursts are an adaptive response to pain that de-synchronizes cortical theta and decreases sensory salience.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 May","modification":"2021-02-21T03:38:40Z","creation":"2019-03-27T02:46:16Z"},"accession":"S-EPMC5449396","cross_references":{"pubmed":["28559582"],"doi":["10.1038/s41598-017-02753-6"]}}