biostudies-literatureDhar DDivision of ChemistryNational Institutes of HealthNIGMS NIH HHS1075-1085https://www.ebi.ac.uk/biostudies/studies/S-EPMC5452261biostudies-literatureUnknown8(2)Kinetic studies of the reactions of two previously characterized copper(iii)-hydroxide complexes (LCuOH and ^NO₂ LCuOH, where L = <i>N</i>,<i>N</i>'-bis(2,6-diisopropylphenyl)-2,6-pyridine-dicarboxamide and ^NO₂ L = <i>N</i>,<i>N</i>'-bis(2,6-diisopropyl-4-nitrophenyl)pyridine-2,6-dicarboxamide) with a series of <i>para</i> substituted phenols (^XArOH where X = NMe₂, OMe, Me, H, Cl, NO₂, or CF₃) were performed using low temperature stopped-flow UV-vis spectroscopy. Second-order rate constants (<i>k</i>) were determined from pseudo first-order and stoichiometric experiments, and follow the trends CF₃ < NO₂ < Cl < H < Me < OMe < NMe₂ and LCuOH < ^NO₂ LCuOChemical scienceReactivity of the copper(iii)-hydroxide unit with phenols.PMC5452261R37 GM047365CHE-12294005R01GM050422R37GM47365R01 GM050422Yee GMTolman WBMayer JMMarkle TFDhar DfalseReactivity of the copper(iii)-hydroxide unit with phenols.Kinetic studies of the reactions of two previously characterized copper(iii)-hydroxide complexes (LCuOH and ^NO₂ LCuOH, where L = <i>N</i>,<i>N</i>'-bis(2,6-diisopropylphenyl)-2,6-pyridine-dicarboxamide and ^NO₂ L = <i>N</i>,<i>N</i>'-bis(2,6-diisopropyl-4-nitrophenyl)pyridine-2,6-dicarboxamide) with a series of <i>para</i> substituted phenols (^XArOH where X = NMe₂, OMe, Me, H, Cl, NO₂, or CF₃) were performed using low temperature stopped-flow UV-vis spectroscopy. Second-order rate constants (<i>k</i>) were determined from pseudo first-order and stoichiometric experiments, and follow the trends CF₃ < NO₂ < Cl < H < Me < OMe < NMe₂ and LCuOH < ^NO₂ LCuO2017-01-01T00:00:00Z2017 Feb2026-05-05T09:48:45.418Z2019-03-27T02:46:27ZS-EPMC54522612857290510.1039/c6sc03039d