{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["96(22)"],"submitter":["Zhuo C"],"pubmed_abstract":["<h4>Background</h4>Parkinson disease (PD) was considered as the 2nd most prevalent neurodegenerative disorder after Alzheimer disease, while depression is a prevailing nonmotor symptom of PD. Typically used antidepression medication includes tricyclic antidepressants (TCA), selective serotonin reuptake inhibitors (SSRI), serotonin and norepinephrine reuptake inhibitors (SNRI), monoamine-oxidase inhibitors (MAOI), and dopamine agonists (DA). Our study aimed at evaluating the efficacy of antidepressive medications for depression of PD.<h4>Methods</h4>Web of Science, PubMed, Embase, and the Cochrane library were searched for related articles. Traditional meta-analysis and network meta-analysis (NMA) were performed with outcomes including depression score, UPDRS-II, UPDRS-III, and adverse effe"],"journal":["Medicine"],"pagination":["e6698"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5459691"],"repository":["biostudies-literature"],"pubmed_title":["Efficacy of antidepressive medication for depression in Parkinson disease: a network meta-analysis."],"pmcid":["PMC5459691"],"pubmed_authors":["Xue R","Ji F","Tian H","Luo L","Lin X","Jiang R","Tao R","Qu H","Zhuo C"],"additional_accession":[]},"is_claimable":false,"name":"Efficacy of antidepressive medication for depression in Parkinson disease: a network meta-analysis.","description":"<h4>Background</h4>Parkinson disease (PD) was considered as the 2nd most prevalent neurodegenerative disorder after Alzheimer disease, while depression is a prevailing nonmotor symptom of PD. Typically used antidepression medication includes tricyclic antidepressants (TCA), selective serotonin reuptake inhibitors (SSRI), serotonin and norepinephrine reuptake inhibitors (SNRI), monoamine-oxidase inhibitors (MAOI), and dopamine agonists (DA). Our study aimed at evaluating the efficacy of antidepressive medications for depression of PD.<h4>Methods</h4>Web of Science, PubMed, Embase, and the Cochrane library were searched for related articles. Traditional meta-analysis and network meta-analysis (NMA) were performed with outcomes including depression score, UPDRS-II, UPDRS-III, and adverse effe","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jun","modification":"2025-04-04T12:29:07.075Z","creation":"2019-03-27T02:46:51Z"},"accession":"S-EPMC5459691","cross_references":{"pubmed":["28562526"],"doi":["10.1097/MD.0000000000006698"]}}