{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Henry MJ"],"pubmed_abstract":["Healthy aging is accompanied by listening difficulties, including decreased speech comprehension, that stem from an ill-understood combination of sensory and cognitive changes. Here, we use electroencephalography to demonstrate that auditory neural oscillations of older adults entrain less firmly and less flexibly to speech-paced (∼3 Hz) rhythms than younger adults' during attentive listening. These neural entrainment effects are distinct in magnitude and origin from the neural response to sound per se. Non-entrained parieto-occipital alpha (8-12 Hz) oscillations are enhanced in young adults, but suppressed in older participants, during attentive listening. Entrained neural phase and task-induced alpha amplitude exert opposite, complementary effects on listening performance: higher alpha amplitude is associated with reduced entrainment-driven behavioural performance modulation. Thus, alpha amplitude as a task-driven, neuro-modulatory signal can counteract the behavioural corollaries of neural entrainment. Balancing these two neural strategies may present new paths for intervention in age-related listening difficulties."],"journal":["Nature communications"],"pagination":["15801"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5490185"],"repository":["biostudies-literature"],"pubmed_title":["Aging affects the balance of neural entrainment and top-down neural modulation in the listening brain."],"pmcid":["PMC5490185"],"pubmed_authors":["Henry MJ","Kunke D","Herrmann B","Obleser J"],"additional_accession":[]},"is_claimable":false,"name":"Aging affects the balance of neural entrainment and top-down neural modulation in the listening brain.","description":"Healthy aging is accompanied by listening difficulties, including decreased speech comprehension, that stem from an ill-understood combination of sensory and cognitive changes. Here, we use electroencephalography to demonstrate that auditory neural oscillations of older adults entrain less firmly and less flexibly to speech-paced (∼3 Hz) rhythms than younger adults' during attentive listening. These neural entrainment effects are distinct in magnitude and origin from the neural response to sound per se. Non-entrained parieto-occipital alpha (8-12 Hz) oscillations are enhanced in young adults, but suppressed in older participants, during attentive listening. Entrained neural phase and task-induced alpha amplitude exert opposite, complementary effects on listening performance: higher alpha amplitude is associated with reduced entrainment-driven behavioural performance modulation. Thus, alpha amplitude as a task-driven, neuro-modulatory signal can counteract the behavioural corollaries of neural entrainment. Balancing these two neural strategies may present new paths for intervention in age-related listening difficulties.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jun","modification":"2025-04-19T13:32:27.058Z","creation":"2019-03-27T02:48:50Z"},"accession":"S-EPMC5490185","cross_references":{"pubmed":["28654081"],"doi":["10.1038/ncomms15801"]}}