{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Gavrilov S"],"funding":["Russian Foundation for Basic Research","Russian Science Foundation"],"pagination":["1228"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5492636"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["8"],"pubmed_abstract":["<i>Melioribacter roseus</i>, a representative of recently proposed Ignavibacteriae phylum, is a metabolically versatile thermophilic bacterium, inhabiting subsurface biosphere of the West-Siberian megabasin and capable of growing on various substrates and electron acceptors. Genomic analysis followed by inhibitor studies and membrane potential measurements of aerobically grown <i>M. roseus</i> cells revealed the activity of aerobic respiratory electron transfer chain comprised of respiratory complexes I and IV, and an alternative complex III. Phylogeny reconstruction revealed that oxygen reductases belonged to atypical <i>cc(o/b)o<sub>3</sub></i> -type and canonical <i>cbb<sub>3</sub></i> -type cytochrome oxidases. Also, two molybdoenzymes of <i>M. roseus</i> were affiliated either with Tt"],"journal":["Frontiers in microbiology"],"pubmed_title":["Respiratory Pathways Reconstructed by Multi-Omics Analysis in <i>Melioribacter roseus</i>, Residing in a Deep Thermal Aquifer of the West-Siberian Megabasin."],"pmcid":["PMC5492636"],"funding_grant_id":["14-24-00165","14-24-00159","14-50-00029","17-04-02173"],"pubmed_authors":["Podosokorskaya O","Muntyan M","Merkel A","Gavrilov S","Altukhov I","Govorun V","Alexeev D","Kublanov I","Khomyakova M","Bonch-Osmolovskaya E","Butenko I"],"additional_accession":[]},"is_claimable":false,"name":"Respiratory Pathways Reconstructed by Multi-Omics Analysis in <i>Melioribacter roseus</i>, Residing in a Deep Thermal Aquifer of the West-Siberian Megabasin.","description":"<i>Melioribacter roseus</i>, a representative of recently proposed Ignavibacteriae phylum, is a metabolically versatile thermophilic bacterium, inhabiting subsurface biosphere of the West-Siberian megabasin and capable of growing on various substrates and electron acceptors. Genomic analysis followed by inhibitor studies and membrane potential measurements of aerobically grown <i>M. roseus</i> cells revealed the activity of aerobic respiratory electron transfer chain comprised of respiratory complexes I and IV, and an alternative complex III. Phylogeny reconstruction revealed that oxygen reductases belonged to atypical <i>cc(o/b)o<sub>3</sub></i> -type and canonical <i>cbb<sub>3</sub></i> -type cytochrome oxidases. Also, two molybdoenzymes of <i>M. roseus</i> were affiliated either with Tt","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017","modification":"2026-05-04T17:12:36.322Z","creation":"2019-03-27T02:49:00Z"},"accession":"S-EPMC5492636","cross_references":{"pubmed":["28713355"],"doi":["10.3389/fmicb.2017.01228"]}}