{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Park HB"],"funding":["National Institute of Animal Science"],"pagination":["1061-1065"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5494477"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["30(8)"],"pubmed_abstract":["<h4>Objective</h4>This study was conducted to locate quantitative trait loci (QTL) influencing fatty acid (FA) composition in a large F<sub>2</sub> intercross between Landrace and Korean native pigs.<h4>Methods</h4>Eighteen FA composition traits were measured in more than 960 F<sub>2</sub> progeny. All experimental animals were genotyped with 165 microsatellite markers located throughout the pig autosomes.<h4>Results</h4>We detected 112 QTLs for the FA composition; Forty seven QTLs reached the genome-wide significant threshold. In particular, we identified a cluster of highly significant QTLs for FA composition on SSC12. QTL for polyunsaturated fatty acid on pig chromosome 12 (<i>F</i>-value = 97.2 under additive and dominance model, nominal p-value 3.6×10<sup>-39</sup>) accounted for 16.9"],"journal":["Asian-Australasian journal of animal sciences"],"pubmed_title":["Genome scan linkage analysis identifies a major quantitative trait loci for fatty acid composition in <i>longissimus dorsi</i> muscle in an F<sub>2</sub> intercross between Landrace and Korean native pigs."],"pmcid":["PMC5494477"],"funding_grant_id":["PJ01010502","PJ01262701"],"pubmed_authors":["Park HB","Yoo CK","Lee JB","Cho IC","Baek KS","Han SH","Lim HT","Shin SM","Kim JH","Son JK"],"additional_accession":[]},"is_claimable":false,"name":"Genome scan linkage analysis identifies a major quantitative trait loci for fatty acid composition in <i>longissimus dorsi</i> muscle in an F<sub>2</sub> intercross between Landrace and Korean native pigs.","description":"<h4>Objective</h4>This study was conducted to locate quantitative trait loci (QTL) influencing fatty acid (FA) composition in a large F<sub>2</sub> intercross between Landrace and Korean native pigs.<h4>Methods</h4>Eighteen FA composition traits were measured in more than 960 F<sub>2</sub> progeny. All experimental animals were genotyped with 165 microsatellite markers located throughout the pig autosomes.<h4>Results</h4>We detected 112 QTLs for the FA composition; Forty seven QTLs reached the genome-wide significant threshold. In particular, we identified a cluster of highly significant QTLs for FA composition on SSC12. QTL for polyunsaturated fatty acid on pig chromosome 12 (<i>F</i>-value = 97.2 under additive and dominance model, nominal p-value 3.6×10<sup>-39</sup>) accounted for 16.9","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Aug","modification":"2025-04-04T11:13:39.998Z","creation":"2019-03-27T02:49:08Z"},"accession":"S-EPMC5494477","cross_references":{"pubmed":["28111443"],"doi":["10.5713/ajas.16.0562"]}}