{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Abernathy J"],"funding":["Soy Aquaculture Alliance","Agricultural Research Service"],"pagination":["e0180972"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5517010"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(7)"],"pubmed_abstract":["Finding suitable alternative protein sources for diets of carnivorous fish species remains a major concern for sustainable aquaculture. Through genetic selection, we created a strain of rainbow trout that outperforms parental lines in utilizing an all-plant protein diet and does not develop enteritis in the distal intestine, as is typical with salmonids on long-term plant protein-based feeds. By incorporating this strain into functional analyses, we set out to determine which genes are critical to plant protein utilization in the absence of gut inflammation. After a 12-week feeding trial with our selected strain and a control trout strain fed either a fishmeal-based diet or an all-plant protein diet, high-throughput RNA sequencing was completed on both liver and muscle tissues. Differentia"],"journal":["PloS one"],"pubmed_title":["Integrative functional analyses using rainbow trout selected for tolerance to plant diets reveal nutrigenomic signatures for soy utilization without the concurrence of enteritis."],"pmcid":["PMC5517010"],"funding_grant_id":["2050-21310-005-00D","UI/2013T01","UI/2013T02"],"pubmed_authors":["Abernathy J","Hardy RW","Brezas A","Snekvik KR","Overturf K"],"additional_accession":[]},"is_claimable":false,"name":"Integrative functional analyses using rainbow trout selected for tolerance to plant diets reveal nutrigenomic signatures for soy utilization without the concurrence of enteritis.","description":"Finding suitable alternative protein sources for diets of carnivorous fish species remains a major concern for sustainable aquaculture. Through genetic selection, we created a strain of rainbow trout that outperforms parental lines in utilizing an all-plant protein diet and does not develop enteritis in the distal intestine, as is typical with salmonids on long-term plant protein-based feeds. By incorporating this strain into functional analyses, we set out to determine which genes are critical to plant protein utilization in the absence of gut inflammation. After a 12-week feeding trial with our selected strain and a control trout strain fed either a fishmeal-based diet or an all-plant protein diet, high-throughput RNA sequencing was completed on both liver and muscle tissues. Differentia","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017","modification":"2026-05-05T19:51:53.841Z","creation":"2019-03-27T02:50:57Z"},"accession":"S-EPMC5517010","cross_references":{"pubmed":["28723948"],"doi":["10.1371/journal.pone.0180972"]}}