{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yang Y"],"funding":["CAMS Innovation Fund for Medical Sciences","National Natural Science Foundation of China"],"pagination":["491-495"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5518643"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(4)"],"pubmed_abstract":["Two new compounds, named lyciumlignan D (<b>1</b>) and lyciumphenyl propanoid A (<b>2</b>), along with seven known compounds, were isolated from the root bark of <i>Lycium chinense</i>. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those of the literature. Compounds <b>3</b>-<b>9</b> were isolated from this genus for the first time. In the <i>in vitro</i> assay, compounds <b>3</b>, <b>6</b>, and <b>7</b> exhibited stronger anti-inflammatory effects than the positive control curcumin at a concentration of 10 μmol/L."],"journal":["Acta pharmaceutica Sinica. B"],"pubmed_title":["Nine compounds from the root bark of <i>Lycium chinense</i> and their anti-inflammatory activitieslammatory activitiesretain-->."],"pmcid":["PMC5518643"],"funding_grant_id":["2016-I2M-1-007","81303207"],"pubmed_authors":["Jiang J","Yang Y","Feng Z","Zhang J","An Y","Wang W","Du N","Zhang P"],"additional_accession":[]},"is_claimable":false,"name":"Nine compounds from the root bark of <i>Lycium chinense</i> and their anti-inflammatory activitieslammatory activitiesretain-->.","description":"Two new compounds, named lyciumlignan D (<b>1</b>) and lyciumphenyl propanoid A (<b>2</b>), along with seven known compounds, were isolated from the root bark of <i>Lycium chinense</i>. Their structures were elucidated using spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, CD), as well as by comparison with those of the literature. Compounds <b>3</b>-<b>9</b> were isolated from this genus for the first time. In the <i>in vitro</i> assay, compounds <b>3</b>, <b>6</b>, and <b>7</b> exhibited stronger anti-inflammatory effects than the positive control curcumin at a concentration of 10 μmol/L.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jul","modification":"2025-04-21T14:39:43.683Z","creation":"2019-03-27T02:51:01Z"},"accession":"S-EPMC5518643","cross_references":{"pubmed":["28752035"],"doi":["10.1016/j.apsb.2017.04.004"]}}