{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nhat NTD"],"funding":["Wellcome Trust"],"pagination":["6060"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5519701"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(1)"],"pubmed_abstract":["Seroepidemiological studies aim to understand population-level exposure and immunity to infectious diseases. Their results are normally presented as binary outcomes describing the presence or absence of pathogen-specific antibody, despite the fact that many assays measure continuous quantities. A population's natural distribution of antibody titers to an endemic infectious disease may include information on multiple serological states - naiveté, recent infection, non-recent infection, childhood infection - depending on the disease in question and the acquisition and waning patterns of immunity. In this study, we investigate 20,152 general-population serum samples from southern Vietnam collected between 2009 and 2013 from which we report antibody titers to the influenza virus HA1 protein us"],"journal":["Scientific reports"],"pubmed_title":["Structure of general-population antibody titer distributions to influenza A virus."],"pmcid":["PMC5519701"],"funding_grant_id":["089276","098511/Z/12/Z","097465/B/11/Z"],"pubmed_authors":["Ha VTH","Quan TM","Thwaites GE","Vy NHT","Thanh NTL","Hung NT","Huy HLA","de Bruin E","Todd S","Thao TTN","Lien NTN","Boni MF","Hong TTK","Lam HM","Anh PH","Nhat NTD","Baker S","Simmons CP","Chau NVV","Koopmans M","Farrar J","Vinh DN","van Beek J"],"additional_accession":[]},"is_claimable":false,"name":"Structure of general-population antibody titer distributions to influenza A virus.","description":"Seroepidemiological studies aim to understand population-level exposure and immunity to infectious diseases. Their results are normally presented as binary outcomes describing the presence or absence of pathogen-specific antibody, despite the fact that many assays measure continuous quantities. A population's natural distribution of antibody titers to an endemic infectious disease may include information on multiple serological states - naiveté, recent infection, non-recent infection, childhood infection - depending on the disease in question and the acquisition and waning patterns of immunity. In this study, we investigate 20,152 general-population serum samples from southern Vietnam collected between 2009 and 2013 from which we report antibody titers to the influenza virus HA1 protein us","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jul","modification":"2025-04-26T12:14:54.417Z","creation":"2019-03-27T02:51:07Z"},"accession":"S-EPMC5519701","cross_references":{"pubmed":["28729702"],"doi":["10.1038/s41598-017-06177-0"]}}