biostudies-literatureBlauwendraat CNational Institute of Neurological Disorders and StrokeNational Institute of Environmental Health SciencesIntramural NIH HHSBundesministerium für Bildung und ForschungParkinson's UKNational Institutes of HealthNational Institute of General Medical SciencesNational Institute on AgingHuffington FoundationEU Joint Programme – Neurodegenerative Disease ResearchBarts CharityU.S. Department of Health and Human ServicesBurroughs Wellcome FundMedical Research CouncilNational Institute for Health Research (NIHR)Muscular Dystrophy UKParkinson's UK247.e9-247.e13https://www.ebi.ac.uk/biostudies/studies/S-EPMC5534378biostudies-literatureUnknown57Genetics has proven to be a powerful approach in neurodegenerative diseases research, resulting in the identification of numerous causal and risk variants. Previously, we introduced the NeuroX Illumina genotyping array, a fast and efficient genotyping platform designed for the investigation of genetic variation in neurodegenerative diseases. Here, we present its updated version, named NeuroChip. The NeuroChip is a low-cost, custom-designed array containing a tagging variant backbone of about 306,670 variants complemented with a manually curated custom content comprised of 179,467 variants implicated in diverse neurological diseases, including Alzheimer's disease, Parkinson's disease, Lewy body dementia, amyotrophic lateral sclerosis, frontotemporal dementia, progressive supranuclear palsy,Neurobiology of agingNeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases.PMC5534378Z99 NS999999NF-SI-0515-10082Z01 AG000949MR/L501554/1MR/K01417X/1MGU0364G0300429G-1107G0802462MR/N008324/1G07009438047Z01-AG000949-02NF-SI-0507-1037616GRO-PS36-0055MC_PC_09003K-1501ACF-2012-17-017MR/L023784/2G1100643MR/L023784/11U54GM114838ZIA NS003154NF-SI-0513-10064J-0804Z01 ES1019861ZIANS003154Z01-ES101986Robak LPihlstrom LGeiger JTWilliams JCampbell RHRyten MHernandez DGMurphy NAGasser TLesage SGuerreiro RBlauwendraat CInternational Parkinson's Disease Genomics Consortium (IPDGC), COURAGE-PD ConsortiumWood NWSims RChung SJBras JFaghri FHardy JALubbe SMay PNicolas AGibbs JRHoulden HRogaeva EFerrari RSingleton ABBrice AShulman JMHeutink PSimon-Sanchez JSharma MChia RTraynor BJAbramzon YCorvol JCMok KYKruger RElbaz AMorris HRNalls MAScholz SWfalseNeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases.Genetics has proven to be a powerful approach in neurodegenerative diseases research, resulting in the identification of numerous causal and risk variants. Previously, we introduced the NeuroX Illumina genotyping array, a fast and efficient genotyping platform designed for the investigation of genetic variation in neurodegenerative diseases. Here, we present its updated version, named NeuroChip. The NeuroChip is a low-cost, custom-designed array containing a tagging variant backbone of about 306,670 variants complemented with a manually curated custom content comprised of 179,467 variants implicated in diverse neurological diseases, including Alzheimer's disease, Parkinson's disease, Lewy body dementia, amyotrophic lateral sclerosis, frontotemporal dementia, progressive supranuclear palsy,2017-01-01T00:00:00Z2017 Sep2026-05-02T09:11:37.702Z2019-03-26T23:53:51ZS-EPMC55343782860250910.1016/j.neurobiolaging.2017.05.009