{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dominguez Coello S"],"funding":["FUNDACION CAJA CANARIAS","Instituto de Salud Carlos III"],"pagination":["369"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5547514"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["18(1)"],"pubmed_abstract":["<h4>Background</h4>Research published to date on the relationship between insulin resistance (IR) and fructose consumption is scarce, has used different methods, and has yielded sometimes contradictory results. This study aims to determine whether a low-fructose and/or low-sucrose diet supervised by a physician or nurse decreases IR compared to a standard diet.<h4>Methods/design</h4>This field trial is located at primary care centers. The participants are adults aged 29 to 66 years, with a Body mass Index (BMI) between 29 and 40.99 kg/m<sup>2</sup> and without diabetes. To date, 245 participants have been assigned randomly to the low-fructose diet intervention group (LFDI) at health centers in the western health service zone of Tenerife island, and 245 to the standard-diet control group (S"],"journal":["Trials"],"pubmed_title":["Effectiveness of a low-fructose and/or low-sucrose diet in decreasing insulin resistance (DISFRUTE study): study protocol for a randomized controlled trial."],"pmcid":["PMC5547514"],"funding_grant_id":["2013/ OBE04","PI12/00231"],"pubmed_authors":["Perez Gonzalez B","Olivares Hernandez N","Moreno Calvo L","Marrero Diaz MD","Ramos Hernandez A","Plasencia Barrera A","Sanchez Perez M","Martel Martell A","Carmona Pinero DE","Sanz Sanchez I","Afonso Luis JM","Cabrera de Leon A","Valcarcel Lopez R","Fernandez Barreto CJ","Suarez Diaz RM","Gonzalez Gonzalez B","Gobierno Hernandez J","Gonzalez Liceran A","Garcia Roger MJ","DISFRUTE Group","Ramos Ramos C","Negrin Torres N","Morales Garcia MP","Carrillo Fernandez L","Fernandez Hernandez JA","Dominguez Coello S","Rodriguez Diaz A","Garcia Morin AC","Sotto Rodriguez S","Garcia Mendez MC","Fuertes Valencia C","Perez Valencia JJ","Salamanca Hernandez JM","Garcia Sanchez-Real B","Exposito Alvarez N","Jimenez Velado C","Fuster Jorge F","Perez Perez G","Perez Cejas AM","Dorta Leon AD","Fernandez Palacio LM","Garcia Dopico JA","Reyes Rodriguez AM","Valdes Bilbao T","Gonzalez Rodriguez U","Herrera Hernandez D","Calvino Oliver M","Higueras Linares T","Diez Martin M","Perez Martin OG","Marrero Delgado RA","Gorrin Vargas G","Rodriguez Santos MC","Rodriguez Lopez F","Brito Cabrera MJ","Orihuela Cabrera E","Delgado Estevez JL","Perez Hernandez MJ","Rodriguez Hage JM","Farrais Villalba S","Diestre Ortin MT","Hernandez Vazquez A","Morales Medina EM","Perez Souto M","Lorenzo Toledo J","Martin Conde J","Mendez Abad M","Aguirre Jaime A","Afonso Navarro C","Dorta Espinero M","Hernandez Lorenzo JR","Gonzalez Torrado P","Milena Jimenez JA","Borges Alamo C","Perez Hernandez LM","Pico Picos M","Ramos Fuentes M","Conde Perez J","Garcia Alvarez R","Puerta Del Castillo E","Garcia Marrero MR","Gomez Lopez OT","Martin Hernandez J","Diaz Gomez D","Munoz Fernandez MV","Ginoves Sierra O","Correa Hernandez C","Lopez Diaz AA","Marquez Garcia JC","Morales Lopez M"],"additional_accession":[]},"is_claimable":false,"name":"Effectiveness of a low-fructose and/or low-sucrose diet in decreasing insulin resistance (DISFRUTE study): study protocol for a randomized controlled trial.","description":"<h4>Background</h4>Research published to date on the relationship between insulin resistance (IR) and fructose consumption is scarce, has used different methods, and has yielded sometimes contradictory results. This study aims to determine whether a low-fructose and/or low-sucrose diet supervised by a physician or nurse decreases IR compared to a standard diet.<h4>Methods/design</h4>This field trial is located at primary care centers. The participants are adults aged 29 to 66 years, with a Body mass Index (BMI) between 29 and 40.99 kg/m<sup>2</sup> and without diabetes. To date, 245 participants have been assigned randomly to the low-fructose diet intervention group (LFDI) at health centers in the western health service zone of Tenerife island, and 245 to the standard-diet control group (S","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Aug","modification":"2025-04-04T01:33:53.342Z","creation":"2019-03-27T02:52:55Z"},"accession":"S-EPMC5547514","cross_references":{"pubmed":["28784181"],"doi":["10.1186/s13063-017-2043-z"]}}