{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bazard P"],"funding":["NIA NIH HHS"],"pagination":["7803"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5552804"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(1)"],"pubmed_abstract":["There is a compelling need for the development of new sensory and neural prosthetic devices which are capable of more precise point stimulation. Current prosthetic devices suffer from the limitation of low spatial resolution due to the non-specific stimulation characteristics of electrical stimulation, i.e., the spread of electric fields generated. We present a visible light stimulation method for modulating the firing patterns of electrically-excitable cells using surface plasmon resonance phenomena. In in-vitro studies using gold (Au) nanoparticle-coated nanoelectrodes, we show that this method (substrate coated with nanoparticles) has the potential for incorporating this new technology into neural stimulation prosthetics, such as cochlear implants for the deaf, with very high spatial re"],"journal":["Scientific reports"],"pubmed_title":["Nanoparticle-based Plasmonic Transduction for Modulation of Electrically Excitable Cells."],"pmcid":["PMC5552804"],"funding_grant_id":["P01 AG009524"],"pubmed_authors":["Walton JP","Frisina RD","Bhethanabotla VR","Bazard P"],"additional_accession":[]},"is_claimable":false,"name":"Nanoparticle-based Plasmonic Transduction for Modulation of Electrically Excitable Cells.","description":"There is a compelling need for the development of new sensory and neural prosthetic devices which are capable of more precise point stimulation. Current prosthetic devices suffer from the limitation of low spatial resolution due to the non-specific stimulation characteristics of electrical stimulation, i.e., the spread of electric fields generated. We present a visible light stimulation method for modulating the firing patterns of electrically-excitable cells using surface plasmon resonance phenomena. In in-vitro studies using gold (Au) nanoparticle-coated nanoelectrodes, we show that this method (substrate coated with nanoparticles) has the potential for incorporating this new technology into neural stimulation prosthetics, such as cochlear implants for the deaf, with very high spatial re","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Aug","modification":"2025-04-05T14:31:34.347Z","creation":"2019-03-27T02:53:17Z"},"accession":"S-EPMC5552804","cross_references":{"pubmed":["28798342"],"doi":["10.1038/s41598-017-08141-4"]}}