biostudies-literatureUnknown16Murdaugh DL<h4>Background</h4>Children with ASD show a unique reading profile characterized by decoding abilities equivalent to verbal abilities, but with lower comprehension skills. Neuroimaging studies have found recruitment of regions primarily associated with visual processing (e.g., fusiform gyrus and medial parietal cortex), but reduced activation in frontal and temporal regions, when reading in adults with ASD. The purpose of this study was to assess neural changes associated with an intense reading intervention program in children with ASD using three fMRI tasks of reading.<h4>Methods</h4>25 children with ASD were randomly assigned to a treatment (ASD-EXP) or waitlist group (ASD-WLC). Children participated in a reading intervention program (4-hour sessions per day, 5 days a week for 10 weeks)NeuroImage. Clinical303-312https://www.ebi.ac.uk/biostudies/studies/S-EPMC5565787biostudies-literatureFrom word reading to multisentence comprehension: Improvements in brain activity in children with autism after reading intervention.PMC5565787Murdaugh DLKana RKO'Kelley SEMaximo JOCordes CEfalseFrom word reading to multisentence comprehension: Improvements in brain activity in children with autism after reading intervention.<h4>Background</h4>Children with ASD show a unique reading profile characterized by decoding abilities equivalent to verbal abilities, but with lower comprehension skills. Neuroimaging studies have found recruitment of regions primarily associated with visual processing (e.g., fusiform gyrus and medial parietal cortex), but reduced activation in frontal and temporal regions, when reading in adults with ASD. The purpose of this study was to assess neural changes associated with an intense reading intervention program in children with ASD using three fMRI tasks of reading.<h4>Methods</h4>25 children with ASD were randomly assigned to a treatment (ASD-EXP) or waitlist group (ASD-WLC). Children participated in a reading intervention program (4-hour sessions per day, 5 days a week for 10 weeks)2017-01-01T00:00:00Z20172025-04-19T03:30:58.756Z2019-03-26T23:38:55ZS-EPMC55657872885609310.1016/j.nicl.2017.08.012