biostudies-literatureVysniauskas AEngineering and Physical Sciences Research Council11001-11010https://www.ebi.ac.uk/biostudies/studies/S-EPMC5575558biostudies-literatureUnknown23(46)Conjugated porphyrin dimers have emerged as versatile viscosity-sensitive fluorophores that are suitable for quantitative measurements of microscopic viscosity by ratiometric and fluorescence lifetime-based methods, in a concentration-independent manner. Here, we investigate the effect of extended conjugation in a porphyrin-dimer structure on their ability to sense viscosity and temperature. We show that the sensitivity of the fluorescence lifetime to temperature is a unique property of only a few porphyrin dimers.Chemistry (Weinheim an der Bergstrasse, Germany)Tuning the Sensitivity of Fluorescent Porphyrin Dimers to Viscosity and Temperature.PMC5575558EP/H018565/1Doctoral Prize StudentshipEP/I003983/1EP/K030760/1Kuimova MKBalaz MAnderson HLDing DVysniauskas AQurashi MBoczarow IfalseTuning the Sensitivity of Fluorescent Porphyrin Dimers to Viscosity and Temperature.Conjugated porphyrin dimers have emerged as versatile viscosity-sensitive fluorophores that are suitable for quantitative measurements of microscopic viscosity by ratiometric and fluorescence lifetime-based methods, in a concentration-independent manner. Here, we investigate the effect of extended conjugation in a porphyrin-dimer structure on their ability to sense viscosity and temperature. We show that the sensitivity of the fluorescence lifetime to temperature is a unique property of only a few porphyrin dimers.2017-01-01T00:00:00Z2017 Aug2025-04-18T19:36:42.767Z2019-03-27T02:54:50ZS-EPMC55755582848098910.1002/chem.201700740