{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dauphinot V"],"funding":["Direction Générale de l&apos;Offre de Soins"],"pagination":["195"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5577682"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["17(1)"],"pubmed_abstract":["<h4>Background</h4>Pharmacotherapy is necessary for the management of many diseases which number increased with aging. However, potentially inappropriate prescriptions and polymedication increases iatrogenic risks and can lead to adverse events. To limit the consequences of potentially harmful prescriptions, optimization of drug prescribing is a major stake of improving quality and safety of care in the elderly. The purpose of the OPTIM study is to study the impact of the optimization of drug prescribing on the evolution of functional autonomy at 18 months of follow-up.<h4>Methods</h4>A multicenter, open-label, Randomized Controlled Trial was designed to assess the impact of an optimization program of drug prescribing consisting in a clinical medication review by a pharmacist, in collabora"],"journal":["BMC geriatrics"],"pubmed_title":["A multi-center, randomized, controlled trial to assess the efficacy of optimization of drug prescribing in an elderly population, at 18 months of follow-up, in the evolution of functional autonomy: the OPTIM study protocol."],"pmcid":["PMC5577682"],"funding_grant_id":["PREPS - 13-0531"],"pubmed_authors":["Krolak-Salmon P","Jean-Bart E","Dauphinot V","Mouchoux C"],"additional_accession":[]},"is_claimable":false,"name":"A multi-center, randomized, controlled trial to assess the efficacy of optimization of drug prescribing in an elderly population, at 18 months of follow-up, in the evolution of functional autonomy: the OPTIM study protocol.","description":"<h4>Background</h4>Pharmacotherapy is necessary for the management of many diseases which number increased with aging. However, potentially inappropriate prescriptions and polymedication increases iatrogenic risks and can lead to adverse events. To limit the consequences of potentially harmful prescriptions, optimization of drug prescribing is a major stake of improving quality and safety of care in the elderly. The purpose of the OPTIM study is to study the impact of the optimization of drug prescribing on the evolution of functional autonomy at 18 months of follow-up.<h4>Methods</h4>A multicenter, open-label, Randomized Controlled Trial was designed to assess the impact of an optimization program of drug prescribing consisting in a clinical medication review by a pharmacist, in collabora","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Aug","modification":"2025-04-25T18:23:33.79Z","creation":"2019-03-27T02:55:00Z"},"accession":"S-EPMC5577682","cross_references":{"pubmed":["28854884"],"doi":["10.1186/s12877-017-0600-7"]}}