{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Sayers A"],"funding":["MRC Fellowship","Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["e014041"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5577889"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(7)"],"pubmed_abstract":["<h4>Objective</h4>This article reviews and compares four commonly used approaches to assess patient responsiveness with a treatment or therapy (return to normal (RTN), minimal important difference (MID), minimal clinically important improvement (MCII), OMERACT-OARSI [Outcome Measures in Rheumatology-Osteoarthris Reseach Society International] (OO)) and demonstrates how each of the methods can be formulated in a multilevel modelling (MLM) framework.<h4>Design</h4>Cohort study.<h4>Setting</h4>A cohort of patients undergoing total hip and knee replacement were recruited from a single UK National Health Service hospital.<h4>Population</h4>400 patients from the Arthroplasty Pain Experience cohort study undergoing total hip (n=210) and knee (n=190) replacement who completed the Intermittent and "],"journal":["BMJ open"],"pubmed_title":["A unified multi-level model approach to assessing patient responsiveness including; return to normal, minimally important differences and minimal clinically important improvement for patient reported outcome measures."],"pmcid":["PMC5577889"],"funding_grant_id":["RP-PG-0407-10070","MR/L01226X/1","NF-SI-0515-10048"],"pubmed_authors":["Sayers A","Gooberman-Hill R","Beard D","Dawson J","Wylde V","Blom AW","Price A","Lenguerrand E"],"additional_accession":[]},"is_claimable":false,"name":"A unified multi-level model approach to assessing patient responsiveness including; return to normal, minimally important differences and minimal clinically important improvement for patient reported outcome measures.","description":"<h4>Objective</h4>This article reviews and compares four commonly used approaches to assess patient responsiveness with a treatment or therapy (return to normal (RTN), minimal important difference (MID), minimal clinically important improvement (MCII), OMERACT-OARSI [Outcome Measures in Rheumatology-Osteoarthris Reseach Society International] (OO)) and demonstrates how each of the methods can be formulated in a multilevel modelling (MLM) framework.<h4>Design</h4>Cohort study.<h4>Setting</h4>A cohort of patients undergoing total hip and knee replacement were recruited from a single UK National Health Service hospital.<h4>Population</h4>400 patients from the Arthroplasty Pain Experience cohort study undergoing total hip (n=210) and knee (n=190) replacement who completed the Intermittent and ","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Jul","modification":"2026-05-05T23:38:41.154Z","creation":"2019-03-26T22:45:42Z"},"accession":"S-EPMC5577889","cross_references":{"pubmed":["28733296"],"doi":["10.1136/bmjopen-2016-014041"]}}