{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(31)"],"submitter":["Klaver CEL"],"pubmed_abstract":["<h4>Objective</h4>Early detection of peritoneal metastases (PM) of colorectal cancer (CRC) is difficult and treatment options at a clinically overt stage are limited. Potentially, adjuvant laparoscopic hyperthermic intraperitoneal chemotherapy (HIPEC) is of value. The aim of this study was to present long term oncological outcomes of a pilot study on adjuvant HIPEC to reduce development of PMCRC, with systematic review of literature.<h4>Methods</h4>Long term oncological outcomes of ten patients who underwent laparoscopic HIPEC within eight weeks after resection of primary CRC in the pilot study were retrospectively collected. A systematic search of literature was performed on studies describing the use of HIPEC in patients with CRC at high risk of developing PM.<h4>Results</h4>The median f"],"journal":["Oncotarget"],"pagination":["51200-51209"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5584242"],"repository":["biostudies-literature"],"pubmed_title":["Colorectal cancer at high risk of peritoneal metastases: long term outcomes of a pilot study on adjuvant laparoscopic HIPEC and future perspectives."],"pmcid":["PMC5584242"],"pubmed_authors":["Bemelman WA","Crezee J","Punt CJA","Stam R","Klaver CEL","Sloothaak DAM","Tanis PJ"],"additional_accession":[]},"is_claimable":false,"name":"Colorectal cancer at high risk of peritoneal metastases: long term outcomes of a pilot study on adjuvant laparoscopic HIPEC and future perspectives.","description":"<h4>Objective</h4>Early detection of peritoneal metastases (PM) of colorectal cancer (CRC) is difficult and treatment options at a clinically overt stage are limited. Potentially, adjuvant laparoscopic hyperthermic intraperitoneal chemotherapy (HIPEC) is of value. The aim of this study was to present long term oncological outcomes of a pilot study on adjuvant HIPEC to reduce development of PMCRC, with systematic review of literature.<h4>Methods</h4>Long term oncological outcomes of ten patients who underwent laparoscopic HIPEC within eight weeks after resection of primary CRC in the pilot study were retrospectively collected. A systematic search of literature was performed on studies describing the use of HIPEC in patients with CRC at high risk of developing PM.<h4>Results</h4>The median f","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Aug","modification":"2026-05-01T08:57:35.995Z","creation":"2019-03-27T02:55:24Z"},"accession":"S-EPMC5584242","cross_references":{"pubmed":["28881641"],"doi":["10.18632/oncotarget.17158"]}}