{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Diaz-Rizo V"],"funding":["Instituto Mexicano del Seguro Social"],"pagination":["e0184056"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5595281"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(9)"],"pubmed_abstract":["<h4>Introduction</h4>There are controversial results about the role of serum leptin and adiponectin levels as biomarkers of the severity of proteinuria in lupus nephritis.<h4>Objective</h4>The aim of this study was to evaluate the relationship between serum leptin and adiponectin levels with severity of proteinuria secondary to lupus nephritis (LN).<h4>Methods</h4>In a cross-sectional study, 103 women with systemic lupus erythematosus (SLE) were evaluated for kidney involvement. We compared 30 SLE patients with LN, all of them with proteinuria, versus 73 SLE patients without renal involvement (no LN). A comprehensive set of clinical and laboratory variables was assessed, including serum levels of leptin and adiponectin by ELISA. Multivariate analyses were used to adjust for potential confo"],"journal":["PloS one"],"pubmed_title":["Serum levels of adiponectin and leptin as biomarkers of proteinuria in lupus nephritis."],"pmcid":["PMC5595281"],"funding_grant_id":["FIS/IMSS/PROT/G11/937"],"pubmed_authors":["Gomez-Banuelos E","Sanchez-Mosco D","Cardona-Munoz EG","Salazar-Paramo M","Vazquez-Del Mercado M","Rodriguez-Jimenez NA","Vazquez-Villegas ML","Diaz-Rizo V","Trujillo X","Fajardo-Robledo NS","Gamez-Nava JI","Huerta M","Perez-Guerrero EE","Gonzalez-Lopez L","Bonilla-Lara D","Saldana-Cruz AM","Cardona-Muller D"],"additional_accession":[]},"is_claimable":false,"name":"Serum levels of adiponectin and leptin as biomarkers of proteinuria in lupus nephritis.","description":"<h4>Introduction</h4>There are controversial results about the role of serum leptin and adiponectin levels as biomarkers of the severity of proteinuria in lupus nephritis.<h4>Objective</h4>The aim of this study was to evaluate the relationship between serum leptin and adiponectin levels with severity of proteinuria secondary to lupus nephritis (LN).<h4>Methods</h4>In a cross-sectional study, 103 women with systemic lupus erythematosus (SLE) were evaluated for kidney involvement. We compared 30 SLE patients with LN, all of them with proteinuria, versus 73 SLE patients without renal involvement (no LN). A comprehensive set of clinical and laboratory variables was assessed, including serum levels of leptin and adiponectin by ELISA. Multivariate analyses were used to adjust for potential confo","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017","modification":"2025-04-22T02:35:54.79Z","creation":"2019-03-27T02:56:06Z"},"accession":"S-EPMC5595281","cross_references":{"pubmed":["28898254"],"doi":["10.1371/journal.pone.0184056"]}}