{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu W"],"funding":["Natural Science Foundation of Jiangxi Province","Science and Technology Commission of Shanghai Municipality","Ministry of Science and Technology of the People&apos;s Republic of China","Natural Science Foundation of Shanghai","National Natural Science Foundation of China","National Science Foundation"],"pagination":["1700191"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5604371"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["4(9)"],"pubmed_abstract":["Precise patterning of biomaterials has widespread applications, including drug release, degradable implants, tissue engineering, and regenerative medicine. Patterning of protein-based microstructures using UV-photolithography has been demonstrated using protein as the resist material. The Achilles heel of existing protein-based biophotoresists is the inevitable wide molecular weight distribution during the protein extraction/regeneration process, hindering their practical uses in the semiconductor industry where reliability and repeatability are paramount. A wafer-scale high resolution patterning of bio-microstructures using well-defined silk fibroin light chain as the resist material is presented showing unprecedent performances. The lithographic and etching performance of silk fibroin li"],"journal":["Advanced science (Weinheim, Baden-Wurttemberg, Germany)"],"pubmed_title":["Precise Protein Photolithography (P<sup>3</sup>): High Performance Biopatterning Using Silk Fibroin Light Chain as the Resist."],"pmcid":["PMC5604371"],"funding_grant_id":["1563422","2016YFA0200800","61574156","61527818","14520720400","16JC1420100","BK20160554","1562915"],"pubmed_authors":["Gilbert Corder SN","Zhang G","Kaplan DL","Liu M","Omenetto FG","Zhang S","Shi Z","Liu W","Zhou Z","Li X","Tabarini J","Tao TH","Dong F","Zhang Y","Cheng L","Lee W","Mao Y"],"additional_accession":[]},"is_claimable":false,"name":"Precise Protein Photolithography (P<sup>3</sup>): High Performance Biopatterning Using Silk Fibroin Light Chain as the Resist.","description":"Precise patterning of biomaterials has widespread applications, including drug release, degradable implants, tissue engineering, and regenerative medicine. Patterning of protein-based microstructures using UV-photolithography has been demonstrated using protein as the resist material. The Achilles heel of existing protein-based biophotoresists is the inevitable wide molecular weight distribution during the protein extraction/regeneration process, hindering their practical uses in the semiconductor industry where reliability and repeatability are paramount. A wafer-scale high resolution patterning of bio-microstructures using well-defined silk fibroin light chain as the resist material is presented showing unprecedent performances. The lithographic and etching performance of silk fibroin li","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Sep","modification":"2025-05-29T19:21:06.672Z","creation":"2025-05-29T19:21:06.672Z"},"accession":"S-EPMC5604371","cross_references":{"pubmed":["28932678"],"doi":["10.1002/advs.201700191"]}}