{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ravikumar R"],"funding":["Hanseo University","Ministry of Science, ICT and Future Planning","National Research Foundation of Korea"],"pagination":["921-926"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5605889"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["25(6)"],"pubmed_abstract":["Novel curcumin (CUR)-loaded cellulose acetate phthalate (CAP) nonwoven electrospun nanofiber (NF) transdermal mat was developed and evaluated for its <i>in vitro</i> CUR diffusion properties. Various CAP solutions from 5 to 20 wt% were tested; 17.5 wt% was found to be a suitable concentration for NF fabrication without defects, such as bubble or ribbon structures. The selected wt% CAP solution was loaded with CUR and electrospun into NFs. The prepared CUR-loaded NFs were characterized using scanning electron microscopy, X-ray diffraction, ultraviolet-visible spectroscopy, thermogravimetric analysis (TGA), and <i>in vitro</i> diffusion studies. The as-prepared fibers demonstrated controlled <i>in vitro</i> transdermal delivery of CUR for up to 24 h."],"journal":["Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society"],"pubmed_title":["Preparation, characterization, and <i>in vitro</i> diffusion study of nonwoven electrospun nanofiber of curcumin-loaded cellulose acetate phthalate polymer."],"pmcid":["PMC5605889"],"funding_grant_id":["2014-004694"],"pubmed_authors":["Ubaidulla U","Tae Jang H","Ganesh M","Young Choi E","Ravikumar R"],"additional_accession":[]},"is_claimable":false,"name":"Preparation, characterization, and <i>in vitro</i> diffusion study of nonwoven electrospun nanofiber of curcumin-loaded cellulose acetate phthalate polymer.","description":"Novel curcumin (CUR)-loaded cellulose acetate phthalate (CAP) nonwoven electrospun nanofiber (NF) transdermal mat was developed and evaluated for its <i>in vitro</i> CUR diffusion properties. Various CAP solutions from 5 to 20 wt% were tested; 17.5 wt% was found to be a suitable concentration for NF fabrication without defects, such as bubble or ribbon structures. The selected wt% CAP solution was loaded with CUR and electrospun into NFs. The prepared CUR-loaded NFs were characterized using scanning electron microscopy, X-ray diffraction, ultraviolet-visible spectroscopy, thermogravimetric analysis (TGA), and <i>in vitro</i> diffusion studies. The as-prepared fibers demonstrated controlled <i>in vitro</i> transdermal delivery of CUR for up to 24 h.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Sep","modification":"2025-04-19T03:34:17.878Z","creation":"2019-03-27T02:56:52Z"},"accession":"S-EPMC5605889","cross_references":{"pubmed":["28951679"],"doi":["10.1016/j.jsps.2017.02.004"]}}