{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12(9)"],"submitter":["Jardel S"],"pubmed_abstract":["<h4>Objective</h4>To assess in clinical practice the frequency and diagnosis associated with the SS-B-positive/SS-A negative autoantibody profile.<h4>Methods</h4>We analyzed a one-year consecutive population of 624 patients referred by clinicians to the immunology laboratory to investigate anti-SS-A and/or anti-SS-B autoantibodies, who were detected using luminex technology. Data were analyzed for patients with isolated anti-SS-B autoantibodies. The clinical characteristics and diagnosis of connective tissue diseases (CTD) were retrieved according to the international criteria.<h4>Results</h4>Among 1173 sera positive for anti-SS-A and/or anti-SS-B autoantibodies from 624 patients, we identified 84 patients (13.5%) that had isolated anti-SS-B. Among the 75 patients positive for anti-SS-B wi"],"journal":["PloS one"],"pagination":["e0185104"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5607193"],"repository":["biostudies-literature"],"pubmed_title":["Isolated positive anti-SS-B autoantibodies are not related to clinical features of systemic autoimmune diseases: Results from a routine population survey."],"pmcid":["PMC5607193"],"pubmed_authors":["Coutant F","Hot A","Durieu I","Lega JC","Jardel S","Tebib J","Cottin V","Reynaud Q","Garnier L","Belot A","Fabien N","Vukusic S","Seve P","Laville M"],"additional_accession":[]},"is_claimable":false,"name":"Isolated positive anti-SS-B autoantibodies are not related to clinical features of systemic autoimmune diseases: Results from a routine population survey.","description":"<h4>Objective</h4>To assess in clinical practice the frequency and diagnosis associated with the SS-B-positive/SS-A negative autoantibody profile.<h4>Methods</h4>We analyzed a one-year consecutive population of 624 patients referred by clinicians to the immunology laboratory to investigate anti-SS-A and/or anti-SS-B autoantibodies, who were detected using luminex technology. Data were analyzed for patients with isolated anti-SS-B autoantibodies. The clinical characteristics and diagnosis of connective tissue diseases (CTD) were retrieved according to the international criteria.<h4>Results</h4>Among 1173 sera positive for anti-SS-A and/or anti-SS-B autoantibodies from 624 patients, we identified 84 patients (13.5%) that had isolated anti-SS-B. Among the 75 patients positive for anti-SS-B wi","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017","modification":"2025-04-18T19:36:44.917Z","creation":"2019-03-27T02:56:57Z"},"accession":"S-EPMC5607193","cross_references":{"pubmed":["28931060"],"doi":["10.1371/journal.pone.0185104"]}}