{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Saldanha IJ"],"funding":["NEI NIH HHS"],"pagination":["933-940"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5625342"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["135(9)"],"pubmed_abstract":["<h4>Importance</h4>Suboptimal overlap in outcomes reported in clinical trials and systematic reviews compromises efforts to compare and summarize results across these studies.<h4>Objectives</h4>To examine the most frequent outcomes used in trials and reviews of the 4 most prevalent eye diseases (age-related macular degeneration [AMD], cataract, diabetic retinopathy [DR], and glaucoma) and the overlap between outcomes in the reviews and the trials included in the reviews.<h4>Design, setting, and participants</h4>This cross-sectional study examined all Cochrane reviews that addressed AMD, cataract, DR, and glaucoma; were published as of July 20, 2016; and included at least 1 trial and the trials included in the reviews. For each disease, a pair of clinical experts independently classified al"],"journal":["JAMA ophthalmology"],"pubmed_title":["Comparison of Clinical Trial and Systematic Review Outcomes for the 4 Most Prevalent Eye Diseases."],"pmcid":["PMC5625342"],"funding_grant_id":["U01 EY020522"],"pubmed_authors":["Saldanha IJ","Jones LS","Coleman AL","Lindsley K","Do DV","Virgili G","Meyerle C","Chuck RS","Jampel HD","Dickersin K"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of Clinical Trial and Systematic Review Outcomes for the 4 Most Prevalent Eye Diseases.","description":"<h4>Importance</h4>Suboptimal overlap in outcomes reported in clinical trials and systematic reviews compromises efforts to compare and summarize results across these studies.<h4>Objectives</h4>To examine the most frequent outcomes used in trials and reviews of the 4 most prevalent eye diseases (age-related macular degeneration [AMD], cataract, diabetic retinopathy [DR], and glaucoma) and the overlap between outcomes in the reviews and the trials included in the reviews.<h4>Design, setting, and participants</h4>This cross-sectional study examined all Cochrane reviews that addressed AMD, cataract, DR, and glaucoma; were published as of July 20, 2016; and included at least 1 trial and the trials included in the reviews. For each disease, a pair of clinical experts independently classified al","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Sep","modification":"2025-05-29T22:09:55.737Z","creation":"2019-03-26T23:55:31Z"},"accession":"S-EPMC5625342","cross_references":{"pubmed":["28772305"],"doi":["10.1001/jamaophthalmol.2017.2583"]}}