{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yeh CN"],"funding":["Chang-Gung Medical Research Project","National Science Council of Taiwan","CGMH_NTHU Joint Research"],"pagination":["174-202"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5633353"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15"],"pubmed_abstract":["The data presented in this article are related to the research article entitled \"Synthesis and Characterization of Boron Fenbufen and its F-18 Labeled Homolog for Boron Neutron Capture Therapy of COX-2 Overexpressed Cholangiocarcinoma\". The contents of the data article include 1) the set up for performing <i>in vitro</i> binding assay, 2) <sup>1</sup>H-, <sup>13</sup>C- and <sup>19</sup>F-NMR of compounds described in main text, 3) HPLC chromatogram of the fluorination mixtures, 4) data of <i>in vitro</i> stability test, cell survival assay, western blot and PCR analysis, 5) the modules for fixing the two CCA rats for BNCT, and 6) bar diagram for tumor reduction using [<sup>18</sup>F]FDG-PET 24 h post treatment with BNCT."],"journal":["Data in brief"],"pubmed_title":["Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog."],"pmcid":["PMC5633353"],"funding_grant_id":["NMRPG3F6021","CMRPG3A0512","CRRPG3F0031","CMRPG3E1612","MOST-105–2314-B-182A-041-MY2","NSC-104–2113-M-007–019","CGTH96N2342E1"],"pubmed_authors":["Chang CW","Huang YC","Chen TW","Yu CS","Chen YR","Yeh CN","Chou YC","Chen MH","Chiang KC","Wang HE","Tien SW","Chung YH","Huang WS"],"additional_accession":[]},"is_claimable":false,"name":"Dataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog.","description":"The data presented in this article are related to the research article entitled \"Synthesis and Characterization of Boron Fenbufen and its F-18 Labeled Homolog for Boron Neutron Capture Therapy of COX-2 Overexpressed Cholangiocarcinoma\". The contents of the data article include 1) the set up for performing <i>in vitro</i> binding assay, 2) <sup>1</sup>H-, <sup>13</sup>C- and <sup>19</sup>F-NMR of compounds described in main text, 3) HPLC chromatogram of the fluorination mixtures, 4) data of <i>in vitro</i> stability test, cell survival assay, western blot and PCR analysis, 5) the modules for fixing the two CCA rats for BNCT, and 6) bar diagram for tumor reduction using [<sup>18</sup>F]FDG-PET 24 h post treatment with BNCT.","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Dec","modification":"2025-04-27T03:53:05.784Z","creation":"2019-03-27T02:58:30Z"},"accession":"S-EPMC5633353","cross_references":{"pubmed":["29021997"],"doi":["10.1016/j.dib.2017.08.048"]}}