biostudies-literatureYeh CNChang-Gung Medical Research ProjectNational Science Council of TaiwanCGMH_NTHU Joint Research174-202https://www.ebi.ac.uk/biostudies/studies/S-EPMC5633353biostudies-literatureUnknown15The data presented in this article are related to the research article entitled "Synthesis and Characterization of Boron Fenbufen and its F-18 Labeled Homolog for Boron Neutron Capture Therapy of COX-2 Overexpressed Cholangiocarcinoma". The contents of the data article include 1) the set up for performing <i>in vitro</i> binding assay, 2) ¹H-, ¹³C- and ¹⁹F-NMR of compounds described in main text, 3) HPLC chromatogram of the fluorination mixtures, 4) data of <i>in vitro</i> stability test, cell survival assay, western blot and PCR analysis, 5) the modules for fixing the two CCA rats for BNCT, and 6) bar diagram for tumor reduction using [¹⁸F]FDG-PET 24 h post treatment with BNCT.Data in briefDataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog.PMC5633353NMRPG3F6021CMRPG3A0512CRRPG3F0031CMRPG3E1612MOST-105–2314-B-182A-041-MY2NSC-104–2113-M-007–019CGTH96N2342E1Chang CWHuang YCChen TWYu CSChen YRYeh CNChou YCChen MHChiang KCWang HETien SWChung YHHuang WSfalseDataset on the synthesis and characterization of boron fenbufen and its F-18 labeled homolog.The data presented in this article are related to the research article entitled "Synthesis and Characterization of Boron Fenbufen and its F-18 Labeled Homolog for Boron Neutron Capture Therapy of COX-2 Overexpressed Cholangiocarcinoma". The contents of the data article include 1) the set up for performing <i>in vitro</i> binding assay, 2) ¹H-, ¹³C- and ¹⁹F-NMR of compounds described in main text, 3) HPLC chromatogram of the fluorination mixtures, 4) data of <i>in vitro</i> stability test, cell survival assay, western blot and PCR analysis, 5) the modules for fixing the two CCA rats for BNCT, and 6) bar diagram for tumor reduction using [¹⁸F]FDG-PET 24 h post treatment with BNCT.2017-01-01T00:00:00Z2017 Dec2025-04-27T03:53:05.784Z2019-03-27T02:58:30ZS-EPMC56333532902199710.1016/j.dib.2017.08.048