biostudies-literatureDavis BJKHHS | National Institutes of HealthJohns Hopkins Environment, Energy, Sustainability & Health Institute FellowshipNational Science Foundation's Water, Climate, and Health Integrative Education and Research TraineeshipJohns Hopkins Center for a Livable Future-Lerner Fellowshipe01147-17https://www.ebi.ac.uk/biostudies/studies/S-EPMC5648905biostudies-literatureUnknown83(21)Vibrio parahaemolyticus naturally occurs in brackish and marine waters and is one of the leading causes of seafood-borne illness. Previous work studying the ecology of V. parahaemolyticus has often been limited in geographic extent and lacked a full range of environmental measures. This study used a unique large data set of surface water samples in the Chesapeake Bay (n = 1,385) collected from 148 monitoring stations from 2007 to 2010. Water was analyzed for more than 20 environmental parameters, with additional meteorological and surrounding land use data. The V. parahaemolyticus-specific genetic markers thermolabile hemolysin (tlh), thermostable direct hemolysin (tdh), and tdh-related hemolysin (trh) were assayed using quantitative PCR (qPCR), and interval-censored regression models withApplied and environmental microbiologyEnvironmental Determinants of Vibrio parahaemolyticus in the Chesapeake Bay.PMC56489051K01OD0199181R01AI123931 −01A11069213Davis MFDePaola ADavis BJKJacobs JMSchwab KJCurriero FCfalseEnvironmental Determinants of Vibrio parahaemolyticus in the Chesapeake Bay.Vibrio parahaemolyticus naturally occurs in brackish and marine waters and is one of the leading causes of seafood-borne illness. Previous work studying the ecology of V. parahaemolyticus has often been limited in geographic extent and lacked a full range of environmental measures. This study used a unique large data set of surface water samples in the Chesapeake Bay (n = 1,385) collected from 148 monitoring stations from 2007 to 2010. Water was analyzed for more than 20 environmental parameters, with additional meteorological and surrounding land use data. The V. parahaemolyticus-specific genetic markers thermolabile hemolysin (tlh), thermostable direct hemolysin (tdh), and tdh-related hemolysin (trh) were assayed using quantitative PCR (qPCR), and interval-censored regression models with2017-01-01T00:00:00Z2017 Nov2025-04-26T08:30:27.122Z2019-03-26T23:28:19ZS-EPMC56489052884254110.1128/AEM.01147-1710.1128/aem.01147-17