biostudies-literatureKelley GANational Institute of General Medical SciencesNIGMS NIH HHS693https://www.ebi.ac.uk/biostudies/studies/S-EPMC5651567biostudies-literatureUnknown17(1)<h4>Background</h4>Conduct a systematic review of previous systematic reviews with meta-analysis to determine the effects of exercise (aerobic, strength or both) on cancer-related-fatigue (CRF) in adults with any type of cancer.<h4>Methods</h4>Systematic reviews with meta-analyses of previous randomized controlled trials published through July of 2016 were included by searching six electronic databases and cross-referencing. Dual-selection and data abstraction were conducted. Methodological quality was assessed using the Assessment of Multiple Systematic Reviews (AMSTAR) instrument. Standardized mean differences (SMD) that were pooled using random-effects models were included as the effect size. In addition, 95% prediction intervals (PI), number needed-to-treat (NNT) and percentile improveBMC cancerExercise and cancer-related fatigue in adults: a systematic review of previous systematic reviews with meta-analyses.PMC5651567U54GM104942U54 GM104942Kelley GAKelley KSfalseExercise and cancer-related fatigue in adults: a systematic review of previous systematic reviews with meta-analyses.<h4>Background</h4>Conduct a systematic review of previous systematic reviews with meta-analysis to determine the effects of exercise (aerobic, strength or both) on cancer-related-fatigue (CRF) in adults with any type of cancer.<h4>Methods</h4>Systematic reviews with meta-analyses of previous randomized controlled trials published through July of 2016 were included by searching six electronic databases and cross-referencing. Dual-selection and data abstraction were conducted. Methodological quality was assessed using the Assessment of Multiple Systematic Reviews (AMSTAR) instrument. Standardized mean differences (SMD) that were pooled using random-effects models were included as the effect size. In addition, 95% prediction intervals (PI), number needed-to-treat (NNT) and percentile improve2017-01-01T00:00:00Z2017 Oct2026-05-06T00:23:50.819Z2019-03-27T02:59:35ZS-EPMC56515672905863110.1186/s12885-017-3687-5