{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rodgers LR"],"funding":["Medical Research Council","National Institute for Health Research (NIHR)","Wellcome Trust"],"pagination":["e017989"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5652624"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["7(10)"],"pubmed_abstract":["<h4>Purpose</h4>This is a retrospective cohort study using observational data from anonymised primary care records. We identify and extract all patients with type 2 diabetes and associated clinical data from the Clinical Practice Research Datalink (CPRD) to inform models of disease progression and stratification of treatment.<h4>Participants</h4>Data were extracted from CPRD on 8 August 2016. The initial data set contained all patients (n=313 485) in the database who had received a type 2 diabetes medication. Criteria were applied to identify and exclude those with type 1 diabetes, polycystic ovarian syndrome or other forms of diabetes (n=40 204), and for data quality control (n=12). We identified 251 338 patients for inclusion in future analyses of diabetes progression and treatment respo"],"journal":["BMJ open"],"pubmed_title":["Cohort profile for the MASTERMIND study: using the Clinical Practice Research Datalink (CPRD) to investigate stratification of response to treatment in patients with type 2 diabetes."],"pmcid":["PMC5652624"],"funding_grant_id":["NF-SI-0611-10219","MR/K005707/1","098395/Z/12/Z","NF-SI-0616-10080","MR/N00633X/1"],"pubmed_authors":["Weedon MN","Hattersley AT","Henley WE","Rodgers LR","Shields BM"],"additional_accession":[]},"is_claimable":false,"name":"Cohort profile for the MASTERMIND study: using the Clinical Practice Research Datalink (CPRD) to investigate stratification of response to treatment in patients with type 2 diabetes.","description":"<h4>Purpose</h4>This is a retrospective cohort study using observational data from anonymised primary care records. We identify and extract all patients with type 2 diabetes and associated clinical data from the Clinical Practice Research Datalink (CPRD) to inform models of disease progression and stratification of treatment.<h4>Participants</h4>Data were extracted from CPRD on 8 August 2016. The initial data set contained all patients (n=313 485) in the database who had received a type 2 diabetes medication. Criteria were applied to identify and exclude those with type 1 diabetes, polycystic ovarian syndrome or other forms of diabetes (n=40 204), and for data quality control (n=12). We identified 251 338 patients for inclusion in future analyses of diabetes progression and treatment respo","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Oct","modification":"2026-07-15T21:31:31.587Z","creation":"2026-07-09T10:14:19.557Z"},"accession":"S-EPMC5652624","cross_references":{"pubmed":["29025846"],"doi":["10.1136/bmjopen-2017-017989"]}}