biostudies-literatureCoppola MNIEHS NIH HHS15522https://www.ebi.ac.uk/biostudies/studies/S-EPMC5686165biostudies-literatureUnknown7(1)Plants actively respond to herbivory by inducing various defense mechanisms in both damaged (locally) and non-damaged tissues (systemically). In addition, it is currently widely accepted that plant-to-plant communication allows specific neighbors to be warned of likely incoming stress (defense priming). Systemin is a plant peptide hormone promoting the systemic response to herbivory in tomato. This 18-aa peptide is also able to induce the release of bioactive Volatile Organic Compounds, thus also promoting the interaction between the tomato and the third trophic level (e.g. predators and parasitoids of insect pests). In this work, using a combination of gene expression (RNA-Seq and qRT-PCR), behavioral and chemical approaches, we demonstrate that systemin triggers metabolic changes of the Scientific reportsPlant-to-plant communication triggered by systemin primes anti-herbivore resistance in tomato.PMC568616527307C2007Vitiello AAvitabile CPennacchio FRao RGuerrieri ECoppola MCorrado GDi Lelio IEsposito FRomanelli AMadonna VCascone PfalsePlant-to-plant communication triggered by systemin primes anti-herbivore resistance in tomato.Plants actively respond to herbivory by inducing various defense mechanisms in both damaged (locally) and non-damaged tissues (systemically). In addition, it is currently widely accepted that plant-to-plant communication allows specific neighbors to be warned of likely incoming stress (defense priming). Systemin is a plant peptide hormone promoting the systemic response to herbivory in tomato. This 18-aa peptide is also able to induce the release of bioactive Volatile Organic Compounds, thus also promoting the interaction between the tomato and the third trophic level (e.g. predators and parasitoids of insect pests). In this work, using a combination of gene expression (RNA-Seq and qRT-PCR), behavioral and chemical approaches, we demonstrate that systemin triggers metabolic changes of the 2017-01-01T00:00:00Z2017 Nov2026-04-29T06:11:14.993Z2026-04-07T14:57:08.742ZS-EPMC56861652913841610.1038/s41598-017-15481-8