{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Nelson MD"],"funding":["NHLBI NIH HHS"],"pagination":["1747-54"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5689082"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["117(11)"],"pubmed_abstract":["Hookah (water pipe) smoking is a major new understudied epidemic affecting youth. Because burning charcoal is used to heat the tobacco product, hookah smoke delivers not only nicotine but also large amounts of charcoal combustion products, including carbon-rich nanoparticles that constitute putative coronary vasoconstrictor stimuli and carbon monoxide, a known coronary vasodilator. We used myocardial contrast echocardiography perfusion imaging with intravenous lipid shelled microbubbles in young adult hookah smokers to determine the net effect of smoking hookah on myocardial blood flow. In 9 hookah smokers (age 27 ± 5 years, mean ± SD), we measured myocardial blood flow velocity (β), myocardial blood volume (A), myocardial blood flow (A × β) as well as myocardial oxygen consumption (MVO2) "],"journal":["The American journal of cardiology"],"pubmed_title":["Acute Effect of Hookah Smoking on the Human Coronary Microcirculation."],"pmcid":["PMC5689082"],"funding_grant_id":["R01 HL130046","R01 HL078610"],"pubmed_authors":["Rezk-Hanna M","Benowitz NL","Nelson MD","Mason OR","Elashoff RM","Lindner JR","Tashkin DP","Victor RG","Rader F","Shidban S","Rosenberry R","Tang X"],"additional_accession":[]},"is_claimable":false,"name":"Acute Effect of Hookah Smoking on the Human Coronary Microcirculation.","description":"Hookah (water pipe) smoking is a major new understudied epidemic affecting youth. Because burning charcoal is used to heat the tobacco product, hookah smoke delivers not only nicotine but also large amounts of charcoal combustion products, including carbon-rich nanoparticles that constitute putative coronary vasoconstrictor stimuli and carbon monoxide, a known coronary vasodilator. We used myocardial contrast echocardiography perfusion imaging with intravenous lipid shelled microbubbles in young adult hookah smokers to determine the net effect of smoking hookah on myocardial blood flow. In 9 hookah smokers (age 27 ± 5 years, mean ± SD), we measured myocardial blood flow velocity (β), myocardial blood volume (A), myocardial blood flow (A × β) as well as myocardial oxygen consumption (MVO2) ","dates":{"release":"2016-01-01T00:00:00Z","publication":"2016 Jun","modification":"2025-04-22T07:44:20.787Z","creation":"2019-03-27T03:02:07Z"},"accession":"S-EPMC5689082","cross_references":{"pubmed":["27067622"],"doi":["10.1016/j.amjcard.2016.03.007"]}}