biostudies-literatureUnknown7(1)Kong TThis study aimed to evaluate the association between the delta neutrophil index (DNI), which reflects immature granulocytes, and the severity of ST-elevation myocardial infarction (STEMI), as well as to determine the significance of the DNI as a prognostic marker for early mortality and other clinical outcomes in patients with STEMI who underwent reperfusion. This retrospective, observational cohort study was conducted using patients prospectively integrated in a critical pathway program for STEMI. We included 842 patients diagnosed with STEMI who underwent primary percutaneous coronary intervention (pPCI). Higher DNI values at time-I (within 2 h of pPCI; hazard ratio [HR], 1.075; 95% confidence interval [CI]: 1.046-1.108; p < 0.001) and time-24 (24 h after admission; HR, 1.066; 95% CI: 1.Scientific reports15718https://www.ebi.ac.uk/biostudies/studies/S-EPMC5691079biostudies-literatureUsefulness of the delta neutrophil index to predict 30-day mortality in patients with ST segment elevation myocardial infarction.PMC5691079Kim THPark YSLee HSPark IHong JHKong TYou JSChung SPLee JWfalseUsefulness of the delta neutrophil index to predict 30-day mortality in patients with ST segment elevation myocardial infarction.This study aimed to evaluate the association between the delta neutrophil index (DNI), which reflects immature granulocytes, and the severity of ST-elevation myocardial infarction (STEMI), as well as to determine the significance of the DNI as a prognostic marker for early mortality and other clinical outcomes in patients with STEMI who underwent reperfusion. This retrospective, observational cohort study was conducted using patients prospectively integrated in a critical pathway program for STEMI. We included 842 patients diagnosed with STEMI who underwent primary percutaneous coronary intervention (pPCI). Higher DNI values at time-I (within 2 h of pPCI; hazard ratio [HR], 1.075; 95% confidence interval [CI]: 1.046-1.108; p < 0.001) and time-24 (24 h after admission; HR, 1.066; 95% CI: 1.2017-01-01T00:00:00Z2017 Nov2025-04-04T14:03:25.554Z2019-03-27T03:02:15ZS-EPMC56910792914699410.1038/s41598-017-15878-5