biostudies-literatureGiordano LAssociazione Italiana per la Ricerca sul Cancro785https://www.ebi.ac.uk/biostudies/studies/S-EPMC5700540biostudies-literatureUnknown17(1)<h4>Background</h4>In recent years growing interest has been posed on alternative ways to screen women for breast cancer involving different imaging techniques or adjusting screening interval by breast cancer risk estimates. A new research area is studying circulating microRNAs as molecular biomarkers potentially useful for non invasive early detection together with the analysis of single-nucleotide polymorphisms (SNPs). The Andromeda study is a prospective cohort study on women attending breast cancer screening in a northern Italian area. The aims of the study are: 1) to define appropriate women risk-based stratifications for personalized screening considering different factors (reproductive, family and biopsy history, breast density, lifestyle habits); 2) to evaluate the diagnostic accurBMC cancerThe ANDROMEDA prospective cohort study: predictive value of combined criteria to tailor breast cancer screening and new opportunities from circulating markers: study protocol.PMC5700540IG 2014 Id 15374Favettini EOstano PFeira SGiordano LDebianchi AVergini VAyoubi SHCasella DPitarella SGiubilato PVicari PMenardi AAndromeda working groupAnatrone CGallo FArtuso FSegnan NCeresa MDotti MFrigerio AMarra VPonti AMello-Grand MMano MPPetracci EPezzana AGregnanin IChiorino GBeraudi MOrtale ASaba FPelosin SDi Stefano FIacazio LGarena FPresti PfalseThe ANDROMEDA prospective cohort study: predictive value of combined criteria to tailor breast cancer screening and new opportunities from circulating markers: study protocol.<h4>Background</h4>In recent years growing interest has been posed on alternative ways to screen women for breast cancer involving different imaging techniques or adjusting screening interval by breast cancer risk estimates. A new research area is studying circulating microRNAs as molecular biomarkers potentially useful for non invasive early detection together with the analysis of single-nucleotide polymorphisms (SNPs). The Andromeda study is a prospective cohort study on women attending breast cancer screening in a northern Italian area. The aims of the study are: 1) to define appropriate women risk-based stratifications for personalized screening considering different factors (reproductive, family and biopsy history, breast density, lifestyle habits); 2) to evaluate the diagnostic accur2017-01-01T00:00:00Z2017 Nov2026-04-30T14:27:03.851Z2019-03-27T03:02:47ZS-EPMC57005402916687810.1186/s12885-017-3784-5