{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(1)"],"submitter":["Nguyen MT"],"funding":["Vietnam National University (VNU-HCM)"],"pubmed_abstract":["<h4>Background</h4>The holistic approach of traditional medicine renders the identification of its mechanisms of action difficult. Microarray technology provides an efficient way to analyze the complex genome-wide gene expression of cells treated with mixtures of medicinal ingredients. We performed transcriptional profiling of MCF-7 cells treated with Nam Dia Long (NDL), a Vietnamese traditional formula, to explore the mechanism of action underlying the apoptosis inducing effect of this formula reported in a previous study.<h4>Methods</h4>MCF-7 cells were treated with aqueous extracts of NDL at the IC<sub>50</sub> concentration for 24, 36 and 48 h. Total RNAs at 24 h and 48 h were subsequently extracted, reverse transcribed and submitted to microarray expression profiling using the Human H"],"journal":["BMC complementary and alternative medicine"],"pagination":["522"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5716261"],"repository":["biostudies-literature"],"pubmed_title":["Nam Dia long, a Vietnamese folk formula, induces apoptosis in MCF-7 cells through various mechanisms of action."],"pmcid":["PMC5716261"],"pubmed_authors":["Ho-Huynh TD","Nguyen MT"],"additional_accession":[]},"is_claimable":false,"name":"Nam Dia long, a Vietnamese folk formula, induces apoptosis in MCF-7 cells through various mechanisms of action.","description":"<h4>Background</h4>The holistic approach of traditional medicine renders the identification of its mechanisms of action difficult. Microarray technology provides an efficient way to analyze the complex genome-wide gene expression of cells treated with mixtures of medicinal ingredients. We performed transcriptional profiling of MCF-7 cells treated with Nam Dia Long (NDL), a Vietnamese traditional formula, to explore the mechanism of action underlying the apoptosis inducing effect of this formula reported in a previous study.<h4>Methods</h4>MCF-7 cells were treated with aqueous extracts of NDL at the IC<sub>50</sub> concentration for 24, 36 and 48 h. Total RNAs at 24 h and 48 h were subsequently extracted, reverse transcribed and submitted to microarray expression profiling using the Human H","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Dec","modification":"2025-04-18T18:05:53.704Z","creation":"2019-03-27T03:03:55Z"},"accession":"S-EPMC5716261","cross_references":{"pubmed":["29202775"],"doi":["10.1186/s12906-017-2027-2"]}}