biostudies-literatureBlackburn JMNIGMS NIH HHS6012-6015https://www.ebi.ac.uk/biostudies/studies/S-EPMC5716482biostudies-literatureUnknown19(21)A general approach to access sulfamate esters through preparation of sulfamic acid salts, subsequent activation with triphenylphosphine ditriflate, and nucleophilic trapping is disclosed. The method proceeds in modest to excellent yields to incorporate nucleophiles derived from aliphatic alcohols and phenols. This approach can be employed to furnish differentially substituted sulfamides.Organic lettersSynthesis of N-Substituted Sulfamate Esters from Sulfamic Acid Salts by Activation with Triphenylphosphine Ditriflate.PMC5716482T32 GM007105Ayer SKBlackburn JMRoizen JLShort MAMuellers TDCastanheiro TfalseSynthesis of N-Substituted Sulfamate Esters from Sulfamic Acid Salts by Activation with Triphenylphosphine Ditriflate.A general approach to access sulfamate esters through preparation of sulfamic acid salts, subsequent activation with triphenylphosphine ditriflate, and nucleophilic trapping is disclosed. The method proceeds in modest to excellent yields to incorporate nucleophiles derived from aliphatic alcohols and phenols. This approach can be employed to furnish differentially substituted sulfamides.2017-01-01T00:00:00Z2017 Nov2020-10-29T12:45:29Z2019-03-27T00:04:54ZS-EPMC57164822904891310.1021/acs.orglett.7b03059