{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["136(24)"],"submitter":["Froehler MT"],"pubmed_abstract":["<h4>Background</h4>Endovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.<h4>Methods</h4>STRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or wit"],"journal":["Circulation"],"pagination":["2311-2321"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC5732640"],"repository":["biostudies-literature"],"pubmed_title":["Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke)."],"pmcid":["PMC5732640"],"pubmed_authors":["Hellinger FR","Peterson EC","Martin JC","Derdeyn CP","Zaidat OO","Asi K","Kallmes DF","Siddiqui AH","Dashti SR","Carpenter J","Jindal G","Chen PR","Saver JL","Haussen DC","Chitale R","English JD","Liebeskind DS","Delgado Almandoz JE","Yao TL","Hassan AE","Starkman S","Grobelny TJ","Jumaa MA","Deshaies EM","Froehler MT","Klucznik RP","Thacker I","Mehta BP","Puri AS","Bozorgchami H","Dumont TM","Sunenshine P","Ecker RD","Schirmer CM","Sauvageau E","Jadhav AP","Badruddin A","Alhajeri A","Maidan L","Suzuki S","STRATIS Investigators","Martin CO","Kaushal R","Gandhi RH","Hussain MS","Taqi MA","McPherson SH","Abou-Chebl A","Nogueira RG","Aziz-Sultan MA","Gupta R","Vora N","Deshmukh V","Yavagal DR","Boulos A","Jahan R","Mueller-Kronast NH","Kvamme P","Fessler RD","Monteith SJ","Baxter BW","Linfante I","Robinson DH","Given CA","Majjhoo A"],"additional_accession":[]},"is_claimable":false,"name":"Interhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke).","description":"<h4>Background</h4>Endovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.<h4>Methods</h4>STRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or wit","dates":{"release":"2017-01-01T00:00:00Z","publication":"2017 Dec","modification":"2026-06-09T06:57:54.357Z","creation":"2026-06-09T03:12:01.61Z"},"accession":"S-EPMC5732640","cross_references":{"pubmed":["28943516"],"doi":["10.1161/CIRCULATIONAHA.117.028920"]}}