biostudies-literatureUnknown136(24)Froehler MT<h4>Background</h4>Endovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.<h4>Methods</h4>STRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or witCirculation2311-2321https://www.ebi.ac.uk/biostudies/studies/S-EPMC5732640biostudies-literatureInterhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke).PMC5732640Hellinger FRPeterson ECMartin JCDerdeyn CPZaidat OOAsi KKallmes DFSiddiqui AHDashti SRCarpenter JJindal GChen PRSaver JLHaussen DCChitale REnglish JDLiebeskind DSDelgado Almandoz JEYao TLHassan AEStarkman SGrobelny TJJumaa MADeshaies EMFroehler MTKlucznik RPThacker IMehta BPPuri ASBozorgchami HDumont TMSunenshine PEcker RDSchirmer CMSauvageau EJadhav APBadruddin AAlhajeri AMaidan LSuzuki SSTRATIS InvestigatorsMartin COKaushal RGandhi RHHussain MSTaqi MAMcPherson SHAbou-Chebl ANogueira RGAziz-Sultan MAGupta RVora NDeshmukh VYavagal DRBoulos AJahan RMueller-Kronast NHKvamme PFessler RDMonteith SJBaxter BWLinfante IRobinson DHGiven CAMajjhoo AfalseInterhospital Transfer Before Thrombectomy Is Associated With Delayed Treatment and Worse Outcome in the STRATIS Registry (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke).<h4>Background</h4>Endovascular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke suffering a large-vessel occlusion, although treatment efficacy is highly time-dependent. We hypothesized that interhospital transfer to endovascular-capable centers would result in treatment delays and worse clinical outcomes compared with direct presentation.<h4>Methods</h4>STRATIS (Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke) was a prospective, multicenter, observational, single-arm study of real-world MT for acute stroke because of anterior-circulation large-vessel occlusion performed at 55 sites over 2 years, including 1000 patients with severe stroke and treated within 8 hours. Patients underwent MT with or wit2017-01-01T00:00:00Z2017 Dec2026-06-09T06:57:54.357Z2026-06-09T03:12:01.61ZS-EPMC57326402894351610.1161/CIRCULATIONAHA.117.028920