biostudies-literatureUnknown7(7)Klein JPGerman Federal Ministry of Health<h4>Objective</h4>This study aims to examine whether the effects of internet interventions for depression generalise to participants recruited in clinical settings.<h4>Design</h4>This study uses subgroup analysis of the results of a randomised, controlled, single-blind trial.<h4>Setting</h4>The study takes place in five diagnostic centres in Germany.<h4>Participants</h4>A total of 1013 people with mild to moderate depressive symptoms were recruited from clinical sources as well as internet forums, statutory insurance companies and other sources.<h4>Interventions</h4>This study uses either care-as-usual alone (control) or a 12-week internet intervention (Deprexis) plus usual care (intervention).<h4>Main outcome measures</h4>The primary outcome measure was self-rated depression severity (PatBMJ opene015391https://www.ebi.ac.uk/biostudies/studies/S-EPMC5734368biostudies-literatureDoes recruitment source moderate treatment effectiveness? A subgroup analysis from the EVIDENT study, a randomised controlled trial of an internet intervention for depressive symptoms.PMC5734368Klein JPGamon CMeyer BLutz WHautzinger MMoritz SSchroder JSpath CHohagen FBerger TVettorazzi EfalseDoes recruitment source moderate treatment effectiveness? A subgroup analysis from the EVIDENT study, a randomised controlled trial of an internet intervention for depressive symptoms.<h4>Objective</h4>This study aims to examine whether the effects of internet interventions for depression generalise to participants recruited in clinical settings.<h4>Design</h4>This study uses subgroup analysis of the results of a randomised, controlled, single-blind trial.<h4>Setting</h4>The study takes place in five diagnostic centres in Germany.<h4>Participants</h4>A total of 1013 people with mild to moderate depressive symptoms were recruited from clinical sources as well as internet forums, statutory insurance companies and other sources.<h4>Interventions</h4>This study uses either care-as-usual alone (control) or a 12-week internet intervention (Deprexis) plus usual care (intervention).<h4>Main outcome measures</h4>The primary outcome measure was self-rated depression severity (Pat2017-01-01T00:00:00Z2017 Jul2026-05-02T09:21:00.924Z2019-03-26T22:50:00ZS-EPMC57343682871021210.1136/bmjopen-2016-015391